STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gabPGamma-aminobutyrate (GABA) permease; High-affinity uptake system for GABA. Functions also as a low-affinity proline importer; Belongs to the amino acid-polyamine-organocation (APC) superfamily. Amino acid transporter (AAT) (TC 2.A.3.1) family. (469 aa)    
Predicted Functional Partners:
yfnB
Putative hydrolase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the HAD-like hydrolase superfamily. YjjG family.
   
  
 0.847
gabD
Succinate-semialdehyde dehydrogenase; Catalyzes the NADP(+) dependent oxidation of succinate semialdehyde to succinate.
 
    
 0.845
ydzX
Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
       0.655
yeaB
Putative cation efflux transporter; Secondary manganese efflux system. May prevent manganese intoxication; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.
  
  
 0.653
yeaC
Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; Belongs to the MoxR family.
  
  
 0.615
gabT
4-aminobutyrate aminotransferase; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type e: enzyme; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
  
  
 0.605
yebA
Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
     
 0.597
nasB
Assimilatory nitrate reductase (electron transfer subunit NasB); Required for nitrate assimilation.
      
 0.573
yhjB
Putative Na+/metabolite cotransporter; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.
   
  
 0.569
yodF
Putative Na+/metabolite permease; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
   
  
 0.558
Your Current Organism:
Bacillus subtilis 168
NCBI taxonomy Id: 224308
Other names: B. subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis 168, Bacillus subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis str. BGSC 1A700
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