node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
comEC | cwlP | BSU25570 | BSU21350 | Dna channel for uptake in competent cells; The comE operon is required for the binding and uptake of transforming DNA. ComEC is required for internalization but is dispensable for DNA binding | Lytic transglycosylase; Belongs to the transglycosylase Slt family | 0.458 |
comEC | recA | BSU25570 | BSU16940 | Dna channel for uptake in competent cells; The comE operon is required for the binding and uptake of transforming DNA. ComEC is required for internalization but is dispensable for DNA binding | Multifunctional protein involved in homologous recombination, DNA repair and competence Can catalyze the hydrolysis of (d)ATP in the presence of single-stranded DNA; prefers dATP at least in vitro, catalyzes the dATP-dependent uptake of single- stranded DNA by duplex DNA, and the dATP-dependent hybridization of homologous single-stranded DNAs (strand exchange) . RecA-ATP cannot catalyze homologous DNA strand exchange; SsbA and DprA activate strand exchange by RecA-ATP . It interacts with LexA causing its activation and leading to its autocatalytic cleavage. Hydrolysis of ATP in the pre [...] | 0.964 |
comEC | uvrC | BSU25570 | BSU28490 | Dna channel for uptake in competent cells; The comE operon is required for the binding and uptake of transforming DNA. ComEC is required for internalization but is dispensable for DNA binding | Excinuclease abc (subunit c); The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision | 0.718 |
comEC | yebC | BSU25570 | BSU06380 | Dna channel for uptake in competent cells; The comE operon is required for the binding and uptake of transforming DNA. ComEC is required for internalization but is dispensable for DNA binding | Uncharacterized protein YebC; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane component | 0.587 |
cwlP | comEC | BSU21350 | BSU25570 | Lytic transglycosylase; Belongs to the transglycosylase Slt family | Dna channel for uptake in competent cells; The comE operon is required for the binding and uptake of transforming DNA. ComEC is required for internalization but is dispensable for DNA binding | 0.458 |
cwlP | recA | BSU21350 | BSU16940 | Lytic transglycosylase; Belongs to the transglycosylase Slt family | Multifunctional protein involved in homologous recombination, DNA repair and competence Can catalyze the hydrolysis of (d)ATP in the presence of single-stranded DNA; prefers dATP at least in vitro, catalyzes the dATP-dependent uptake of single- stranded DNA by duplex DNA, and the dATP-dependent hybridization of homologous single-stranded DNAs (strand exchange) . RecA-ATP cannot catalyze homologous DNA strand exchange; SsbA and DprA activate strand exchange by RecA-ATP . It interacts with LexA causing its activation and leading to its autocatalytic cleavage. Hydrolysis of ATP in the pre [...] | 0.662 |
cwlP | scpA | BSU21350 | BSU23220 | Lytic transglycosylase; Belongs to the transglycosylase Slt family | Chromosome condensation and partitioning factor; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves | 0.624 |
cwlP | yebC | BSU21350 | BSU06380 | Lytic transglycosylase; Belongs to the transglycosylase Slt family | Uncharacterized protein YebC; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane component | 0.592 |
cydB | yebC | BSU38750 | BSU06380 | Cytochrome bd ubiquinol oxidase subunit 2; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme | Uncharacterized protein YebC; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane component | 0.619 |
pth | recA | BSU00530 | BSU16940 | Peptidyl-trna hydrolase, pth1 family; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis | Multifunctional protein involved in homologous recombination, DNA repair and competence Can catalyze the hydrolysis of (d)ATP in the presence of single-stranded DNA; prefers dATP at least in vitro, catalyzes the dATP-dependent uptake of single- stranded DNA by duplex DNA, and the dATP-dependent hybridization of homologous single-stranded DNAs (strand exchange) . RecA-ATP cannot catalyze homologous DNA strand exchange; SsbA and DprA activate strand exchange by RecA-ATP . It interacts with LexA causing its activation and leading to its autocatalytic cleavage. Hydrolysis of ATP in the pre [...] | 0.519 |
pth | yebC | BSU00530 | BSU06380 | Peptidyl-trna hydrolase, pth1 family; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis | Uncharacterized protein YebC; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane component | 0.871 |
pth | yrdC | BSU00530 | BSU26760 | Peptidyl-trna hydrolase, pth1 family; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis | Hypothetical protein; Belongs to the isochorismatase family | 0.459 |
recA | comEC | BSU16940 | BSU25570 | Multifunctional protein involved in homologous recombination, DNA repair and competence Can catalyze the hydrolysis of (d)ATP in the presence of single-stranded DNA; prefers dATP at least in vitro, catalyzes the dATP-dependent uptake of single- stranded DNA by duplex DNA, and the dATP-dependent hybridization of homologous single-stranded DNAs (strand exchange) . RecA-ATP cannot catalyze homologous DNA strand exchange; SsbA and DprA activate strand exchange by RecA-ATP . It interacts with LexA causing its activation and leading to its autocatalytic cleavage. Hydrolysis of ATP in the pre [...] | Dna channel for uptake in competent cells; The comE operon is required for the binding and uptake of transforming DNA. ComEC is required for internalization but is dispensable for DNA binding | 0.964 |
recA | cwlP | BSU16940 | BSU21350 | Multifunctional protein involved in homologous recombination, DNA repair and competence Can catalyze the hydrolysis of (d)ATP in the presence of single-stranded DNA; prefers dATP at least in vitro, catalyzes the dATP-dependent uptake of single- stranded DNA by duplex DNA, and the dATP-dependent hybridization of homologous single-stranded DNAs (strand exchange) . RecA-ATP cannot catalyze homologous DNA strand exchange; SsbA and DprA activate strand exchange by RecA-ATP . It interacts with LexA causing its activation and leading to its autocatalytic cleavage. Hydrolysis of ATP in the pre [...] | Lytic transglycosylase; Belongs to the transglycosylase Slt family | 0.662 |
recA | pth | BSU16940 | BSU00530 | Multifunctional protein involved in homologous recombination, DNA repair and competence Can catalyze the hydrolysis of (d)ATP in the presence of single-stranded DNA; prefers dATP at least in vitro, catalyzes the dATP-dependent uptake of single- stranded DNA by duplex DNA, and the dATP-dependent hybridization of homologous single-stranded DNAs (strand exchange) . RecA-ATP cannot catalyze homologous DNA strand exchange; SsbA and DprA activate strand exchange by RecA-ATP . It interacts with LexA causing its activation and leading to its autocatalytic cleavage. Hydrolysis of ATP in the pre [...] | Peptidyl-trna hydrolase, pth1 family; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis | 0.519 |
recA | uvrC | BSU16940 | BSU28490 | Multifunctional protein involved in homologous recombination, DNA repair and competence Can catalyze the hydrolysis of (d)ATP in the presence of single-stranded DNA; prefers dATP at least in vitro, catalyzes the dATP-dependent uptake of single- stranded DNA by duplex DNA, and the dATP-dependent hybridization of homologous single-stranded DNAs (strand exchange) . RecA-ATP cannot catalyze homologous DNA strand exchange; SsbA and DprA activate strand exchange by RecA-ATP . It interacts with LexA causing its activation and leading to its autocatalytic cleavage. Hydrolysis of ATP in the pre [...] | Excinuclease abc (subunit c); The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision | 0.962 |
recA | yebC | BSU16940 | BSU06380 | Multifunctional protein involved in homologous recombination, DNA repair and competence Can catalyze the hydrolysis of (d)ATP in the presence of single-stranded DNA; prefers dATP at least in vitro, catalyzes the dATP-dependent uptake of single- stranded DNA by duplex DNA, and the dATP-dependent hybridization of homologous single-stranded DNAs (strand exchange) . RecA-ATP cannot catalyze homologous DNA strand exchange; SsbA and DprA activate strand exchange by RecA-ATP . It interacts with LexA causing its activation and leading to its autocatalytic cleavage. Hydrolysis of ATP in the pre [...] | Uncharacterized protein YebC; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane component | 0.516 |
scpA | cwlP | BSU23220 | BSU21350 | Chromosome condensation and partitioning factor; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves | Lytic transglycosylase; Belongs to the transglycosylase Slt family | 0.624 |
scpA | yebC | BSU23220 | BSU06380 | Chromosome condensation and partitioning factor; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves | Uncharacterized protein YebC; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane component | 0.642 |
uvrC | comEC | BSU28490 | BSU25570 | Excinuclease abc (subunit c); The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision | Dna channel for uptake in competent cells; The comE operon is required for the binding and uptake of transforming DNA. ComEC is required for internalization but is dispensable for DNA binding | 0.718 |