Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
yerDPutative flavoenzyme; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme. (525 aa)    
Predicted Functional Partners:
gltB
Glutamate synthase (small subunit); Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme.
 
 0.967
gltA
Glutamate synthase (large subunit); Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the glutamate synthase family.
 
 
0.954
yfkM
General stress protein 18; Functions in the protection against aldehyde-stress, possibly by degrading damaged proteins.
   
 
 0.601
bmrU
Putative lipid kinase BmrU; May catalyze the ATP-dependent phosphorylation of lipids other than diacylglycerol (DAG). In fact, is not able to exhibit diacylglycerol kinase activity in vitro.
  
  
 0.586
ybyB
Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
   
  
 0.569
sapB
Membrane component; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type ph: phenotype.
  
    0.562
ywtG
Putative carbohydrate transporter; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.
   
  
 0.561
guaA
GMP synthetase; Catalyzes the synthesis of GMP from XMP.
  
  
 0.536
csbC
Putative sugar transporter; Could serve either a nutritional or an osmotic protection function; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
   
  
 0.534
cypC
Fatty acid beta-hydroxylating cytochrome P450; Catalyzes the alpha- and beta-hydroxylation of myristic acid in the presence of hydrogen peroxide; Belongs to the cytochrome P450 family.
   
  
 0.517
Your Current Organism:
Bacillus subtilis 168
NCBI taxonomy Id: 224308
Other names: B. subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis 168, Bacillus subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis str. BGSC 1A700
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