Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
yesLPutative permease; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter. (209 aa)    
Predicted Functional Partners:
rhgW
Rhamnogalacturonan endolyase; Pectinolytic enzyme that degrades type I rhamnogalacturonan from plant cell walls and releases oligosaccharide products. Degrades rhamnogalacturonan, polygalacturonic acid, pectic acid and pectin ; Belongs to the polysaccharide lyase 11 family.
  
  
 0.984
yesM
Two-component sensor histidine kinase [YesN]; Member of the two-component regulatory system YesM/YesN. Probably activates YesN by phosphorylation.
 
  
 0.945
yesN
Two-component response regulator [YesM]; Member of the two-component regulatory system YesM/YesN.
 
  
 0.838
lplA
Lipoprotein; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type lp: lipoprotein.
 
    0.708
yesO
Pectin degradation byproducts-binding lipoprotein; May play a role in the degradation of type I rhamnogalacturonan derived from plant cell walls. Belongs to the bacterial solute-binding protein 1 family.
 
    0.668
ytcQ
Putative ABC transporter (binding lipoprotein); Probably part of a binding-protein-dependent transport system; Belongs to the bacterial solute-binding protein 1 family.
 
    0.663
yesJ
Putative acetyltransferase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the acetyltransferase family.
 
    0.618
yesV
Putative integral inner membrane component; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane component.
 
   
0.608
rhgQ
Rhamnogalacturonan permease; Part of a binding-protein-dependent transport system. Probably responsible for the translocation of the substrate across the membrane (By similarity); Belongs to the binding-protein-dependent transport system permease family. MalFG subfamily.
  
  
 0.605
araR
Transcriptional repressor of the ara regulon (LacI family); Transcriptional repressor of the arabinose utilization genes. Also regulates its own expression. Binds to two sequences within the promoters of the araABDLMNPQ-abfA operon and the araE gene, and to one sequence in the araR promoter.
      
 0.567
Your Current Organism:
Bacillus subtilis 168
NCBI taxonomy Id: 224308
Other names: B. subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis 168, Bacillus subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis str. BGSC 1A700
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