node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
mccA | yezD | BSU27260 | BSU07190 | Cystathionine beta-synthase for the reverse transsulfuration pathway; Catalyzes the conversion of O-acetylserine and homocysteine to cystathionine. | Putative paralog of RsbR; Evidence 7: Gene remnant; Product type pr: putative regulator. | 0.543 |
mccA | yrhC | BSU27260 | BSU27240 | Cystathionine beta-synthase for the reverse transsulfuration pathway; Catalyzes the conversion of O-acetylserine and homocysteine to cystathionine. | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 17056751. | 0.950 |
mccA | yrrT | BSU27260 | BSU27280 | Cystathionine beta-synthase for the reverse transsulfuration pathway; Catalyzes the conversion of O-acetylserine and homocysteine to cystathionine. | Putative AdoMet-dependent methyltransferase; Could be a S-adenosyl-L-methionine-dependent methyltransferase; Belongs to the methyltransferase superfamily. YrrT family. | 0.996 |
mccA | ytlI | BSU27260 | BSU29400 | Cystathionine beta-synthase for the reverse transsulfuration pathway; Catalyzes the conversion of O-acetylserine and homocysteine to cystathionine. | Transcriptional regulator (LysR family); Positively regulates the expression of ytmI operon in response to the availability of sulfur sources. | 0.597 |
mccA | yxeK | BSU27260 | BSU39520 | Cystathionine beta-synthase for the reverse transsulfuration pathway; Catalyzes the conversion of O-acetylserine and homocysteine to cystathionine. | Putative monooxygenase; Probably catalyzes the oxygenation of the 2-position of the succinyl moiety of N-acetyl-S-(2-succino)cysteine, causing a spontaneous elimination reaction of the resulting hemithioketal that generates oxaloacetate and N-acetylcysteine (NAC). Is involved in a S- (2-succino)cysteine (2SC) degradation pathway that allows B.subtilis to grow on 2SC as a sole sulfur source, via its metabolization to cysteine; Belongs to the NtaA/SnaA/SoxA(DszA) monooxygenase family. | 0.501 |
mccA | yxeL | BSU27260 | BSU39510 | Cystathionine beta-synthase for the reverse transsulfuration pathway; Catalyzes the conversion of O-acetylserine and homocysteine to cystathionine. | Putative acetyltransferase; Catalyzes the N-acetylation of S-(2-succino)cysteine. Is involved in a S-(2-succino)cysteine (2SC) degradation pathway that allows B.subtilis to grow on 2SC as a sole sulfur source, via its metabolization to cysteine. Moreover, 2SC is a toxic compound in B.subtilis at high exogenous concentrations, and this enzyme relieves 2SC toxicity via N-acetylation; Belongs to the acetyltransferase family. | 0.510 |
mccA | yxeM | BSU27260 | BSU39500 | Cystathionine beta-synthase for the reverse transsulfuration pathway; Catalyzes the conversion of O-acetylserine and homocysteine to cystathionine. | Putative ABC transporter (binding lipoprotein); Probably part of the ABC transporter complex YxeMNO that could be involved in amino-acid import. May transport S-methylcysteine; Belongs to the bacterial solute-binding protein 3 family. | 0.538 |
mccA | yxeN | BSU27260 | BSU39490 | Cystathionine beta-synthase for the reverse transsulfuration pathway; Catalyzes the conversion of O-acetylserine and homocysteine to cystathionine. | Putative ABC transporter (permease); Probably part of the ABC transporter complex YxeMNO that could be involved in amino-acid import. May transport S-methylcysteine. Probably responsible for the translocation of the substrate across the membrane (Probable); Belongs to the binding-protein-dependent transport system permease family. | 0.615 |
mccA | yxeO | BSU27260 | BSU39480 | Cystathionine beta-synthase for the reverse transsulfuration pathway; Catalyzes the conversion of O-acetylserine and homocysteine to cystathionine. | Putative ABC transporter (ATP-binding protein); Probably part of the ABC transporter complex YxeMNO that could be involved in amino-acid import. May transport S-methylcysteine. Responsible for energy coupling to the transport system (Probable). | 0.504 |
yezD | mccA | BSU07190 | BSU27260 | Putative paralog of RsbR; Evidence 7: Gene remnant; Product type pr: putative regulator. | Cystathionine beta-synthase for the reverse transsulfuration pathway; Catalyzes the conversion of O-acetylserine and homocysteine to cystathionine. | 0.543 |
yezD | yisJ | BSU07190 | BSU10740 | Putative paralog of RsbR; Evidence 7: Gene remnant; Product type pr: putative regulator. | Putative spore coat protein; Involved in the assembly of several proteins in the inner and outer layer of the spore coat; Belongs to the CotH family. | 0.750 |
yezD | yrhC | BSU07190 | BSU27240 | Putative paralog of RsbR; Evidence 7: Gene remnant; Product type pr: putative regulator. | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 17056751. | 0.778 |
yezD | yrrT | BSU07190 | BSU27280 | Putative paralog of RsbR; Evidence 7: Gene remnant; Product type pr: putative regulator. | Putative AdoMet-dependent methyltransferase; Could be a S-adenosyl-L-methionine-dependent methyltransferase; Belongs to the methyltransferase superfamily. YrrT family. | 0.794 |
yezD | ytlI | BSU07190 | BSU29400 | Putative paralog of RsbR; Evidence 7: Gene remnant; Product type pr: putative regulator. | Transcriptional regulator (LysR family); Positively regulates the expression of ytmI operon in response to the availability of sulfur sources. | 0.680 |
yezD | yxeK | BSU07190 | BSU39520 | Putative paralog of RsbR; Evidence 7: Gene remnant; Product type pr: putative regulator. | Putative monooxygenase; Probably catalyzes the oxygenation of the 2-position of the succinyl moiety of N-acetyl-S-(2-succino)cysteine, causing a spontaneous elimination reaction of the resulting hemithioketal that generates oxaloacetate and N-acetylcysteine (NAC). Is involved in a S- (2-succino)cysteine (2SC) degradation pathway that allows B.subtilis to grow on 2SC as a sole sulfur source, via its metabolization to cysteine; Belongs to the NtaA/SnaA/SoxA(DszA) monooxygenase family. | 0.635 |
yezD | yxeL | BSU07190 | BSU39510 | Putative paralog of RsbR; Evidence 7: Gene remnant; Product type pr: putative regulator. | Putative acetyltransferase; Catalyzes the N-acetylation of S-(2-succino)cysteine. Is involved in a S-(2-succino)cysteine (2SC) degradation pathway that allows B.subtilis to grow on 2SC as a sole sulfur source, via its metabolization to cysteine. Moreover, 2SC is a toxic compound in B.subtilis at high exogenous concentrations, and this enzyme relieves 2SC toxicity via N-acetylation; Belongs to the acetyltransferase family. | 0.599 |
yezD | yxeM | BSU07190 | BSU39500 | Putative paralog of RsbR; Evidence 7: Gene remnant; Product type pr: putative regulator. | Putative ABC transporter (binding lipoprotein); Probably part of the ABC transporter complex YxeMNO that could be involved in amino-acid import. May transport S-methylcysteine; Belongs to the bacterial solute-binding protein 3 family. | 0.621 |
yezD | yxeN | BSU07190 | BSU39490 | Putative paralog of RsbR; Evidence 7: Gene remnant; Product type pr: putative regulator. | Putative ABC transporter (permease); Probably part of the ABC transporter complex YxeMNO that could be involved in amino-acid import. May transport S-methylcysteine. Probably responsible for the translocation of the substrate across the membrane (Probable); Belongs to the binding-protein-dependent transport system permease family. | 0.587 |
yezD | yxeO | BSU07190 | BSU39480 | Putative paralog of RsbR; Evidence 7: Gene remnant; Product type pr: putative regulator. | Putative ABC transporter (ATP-binding protein); Probably part of the ABC transporter complex YxeMNO that could be involved in amino-acid import. May transport S-methylcysteine. Responsible for energy coupling to the transport system (Probable). | 0.545 |
yisJ | yezD | BSU10740 | BSU07190 | Putative spore coat protein; Involved in the assembly of several proteins in the inner and outer layer of the spore coat; Belongs to the CotH family. | Putative paralog of RsbR; Evidence 7: Gene remnant; Product type pr: putative regulator. | 0.750 |