STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yfnCMfs transporter, fsr family, fosmidomycin resistance protein; Uncharacterized MFS-type transporter YfnC; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter (409 aa)    
Predicted Functional Partners:
hmp
Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
  
  
 0.634
gltA
Glutamate synthase (nadph) large chain; Belongs to the glutamate synthase family
      
 0.582
nasF
Uroporphyrinogen iii methyltransferase / synthase; Belongs to the precorrin methyltransferase family
  
  
 0.559
yfnB
2-haloacid dehalogenase; Belongs to the HAD-like hydrolase superfamily. YjjG family
       0.559
narJ
Chaperone required for proper molybdenum cofactor insertion and final assembly of the membrane-bound respiratory nitrate reductase
  
  
 0.539
ydeK
Uncharacterized transporter YdeK; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter
  
     0.471
nasE
Assimilatory nitrite reductase [nad(p)h] small subunit; Required for nitrite assimilation. Required for activity of the reductase (By similarity)
  
  
 0.461
narG
Nitrate reductase / nitrite oxidoreductase, alpha subunit; The alpha chain is the actual site of nitrate reduction
  
  
 0.456
sirB
Sirohydrochlorin ferrochelatase; Chelates iron to the siroheme precursor
  
    0.424
narH
Nitrate reductase / nitrite oxidoreductase, beta subunit; The beta chain is an electron transfer unit containing four cysteine clusters involved in the formation of iron-sulfur centers. Electrons are transferred from the gamma chain to the molybdenum cofactor of the alpha subunit
  
 
 0.409
Your Current Organism:
Bacillus subtilis
NCBI taxonomy Id: 224308
Other names: B. subtilis subsp. subtilis str. 168, Bacillus subtilis 168, Bacillus subtilis subsp. subtilis 168, Bacillus subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis str. BGSC 1A700
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