Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
yflIConserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. (51 aa)    
Predicted Functional Partners:
yraO
Putative citrate transporter; Transports the free citrate anion; Belongs to the CitM (TC 2.A.11) transporter family.
      
 0.876
yyaO
Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
   
  
 0.782
ykqA
Conserved hypothetical protein; Putative gamma-glutamylcyclotransferase.
      
 0.748
yyaN
Putative transcriptional regulator (MerR family); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.
      
 0.742
yflH
Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 1070366, 1266368.
  
    0.559
yflJ
Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
  
    0.515
yxiE
Phosphate starvation protein (universal stress protein A family); Evidence 1a: Function experimentally demonstrated in the studied strain; Product type f: factor; Belongs to the universal stress protein A family.
      
 0.407
mapB
Methionine aminopeptidase B; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.
  
    0.405
Your Current Organism:
Bacillus subtilis 168
NCBI taxonomy Id: 224308
Other names: B. subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis 168, Bacillus subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis str. BGSC 1A700
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