STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yfjAConserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; Belongs to the WXG100 family. (104 aa)    
Predicted Functional Partners:
yukB
Putative cell division protein; Required for YukE secretion. Probable component or regulator of the ESX/ESAT-6-like secretion system (BsEss).
  
 
 0.965
yfjB
Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
  
    0.936
yfjC
Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
  
    0.933
yukE
Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 15576783.
   
  
 0.922
yukC
Putative membrane-associated enzyme involved in bacteriocin production; Required for YukE secretion. Probable component or regulator of the ESX/ESAT-6-like secretion system (BsEss).
  
  
 0.881
yfjD
Putative integral inner membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane component.
  
    0.872
yfjE
Putative integral inner membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane component.
  
    0.794
yueC
Hypothetical protein; Required for YukE secretion. Probable component or regulator of the ESX/ESAT-6-like secretion system (BsEss).
  
  
 0.775
yukD
Putative bacteriocin; Required for YukE secretion. Probable component or regulator of the ESX/ESAT-6-like secretion system (BsEss). Belongs to the EsaB family.
  
  
 0.736
spoIIIE
Spore DNA translocase; Plays an essential role during sporulation. Required for the translocation of the chromosomal DNA from mother cell into the forespore during polar septation, for the final steps of compartmentalization in the presence of trapped DNA, and for the final steps of engulfment. The N-terminus mediates localization to the division septum and is required for both septal membrane fusion and engulfment membrane fusion. May form DNA-conducting channels across the two lipid bilayers of the septum after cell division. The C-terminus functions as a DNA motor that exports DNA i [...]
  
 
 0.640
Your Current Organism:
Bacillus subtilis 168
NCBI taxonomy Id: 224308
Other names: B. subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis 168, Bacillus subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis str. BGSC 1A700
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.