STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
malQMaltose and maltodextrin ABC transporter subunit (ATP-binding protein); Evidence 1a: Function experimentally demonstrated in the studied strain; Product type t: transporter. (573 aa)    
Predicted Functional Partners:
yfiC
Putative ABC transporter (ATP-binding protein); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.
 
   
0.933
malP
Phosphotransferase system (PTS) maltose-specific enzyme IICB component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in maltose transport.
  
  
 0.877
ythA
Putative cytochrome bd menaquinol oxidase subunit I; May have a role in sporulation. Can compensate for the loss of cytochrome aa3; Belongs to the cytochrome ubiquinol oxidase subunit 1 family.
   
  
 0.854
sunT
Sublancin 168 lantibiotic transporter; SunT (TC 3.A.1.112.4) is required for production of the lantibiotic sublancin-168, probably by both processing the signal peptide and exporting the resulting mature lantibiotic.
 
 
  
0.664
yknY
Putative ABC transporter (ATP-binding protein); Part of an unusual four-component transporter, which is required for protection against the killing factor SdpC (sporulation- delaying protein).
     
0.642
pksJ
Polyketide synthase of type I; Involved in some intermediate steps for the synthesis of the antibiotic polyketide bacillaene which is involved in secondary metabolism.
  
 0.577
pksN
Polyketide synthase of type I; Involved in some intermediate steps for the synthesis of the antibiotic polyketide bacillaene which is involved in secondary metabolism.
  
 0.577
srfAB
Surfactin synthetase; This protein is a multifunctional enzyme able to activate and polymerize the amino acids Leu, Glu, Asp and Val. Activation sites for these AA consist of individual domains.
  
 
 0.554
malR
Transcriptional activator of the Mal operon; Positive regulator of the glv operon expression, which consists of GlvA, GlvR and GlvC.
  
    0.500
fbpC
Regulator of iron homeostasis; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type r: regulator.
      
 0.487
Your Current Organism:
Bacillus subtilis 168
NCBI taxonomy Id: 224308
Other names: B. subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis 168, Bacillus subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis str. BGSC 1A700
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