STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
padRTranscriptional regulator of PadC; Negative transcriptional regulator of padC phenolic acid decarboxylase. (182 aa)    
Predicted Functional Partners:
padC
Phenolic acid decarboxylase; Involved in the decarboxylation and detoxification of phenolic derivatives. It is able to catalyze the decarboxylation of ferulic, p-coumaric and caffeic acids; Belongs to the PadC family.
 
  
 0.988
arsR
Transcriptional regulator (ArsR family); Transcriptional repressor for the ars operon.
      
 0.775
yveG
Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; Belongs to the UPF0311 family.
 
  
 0.770
ywzG
Putative transcriptional regulator, PadR family; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: putative regulator.
      
 0.746
yveF
Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
      
 0.714
qdoR
Transcriptional regulator; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type r: regulator.
  
  
 0.627
fapR
Transcription factor controlling fatty acid and phospholipid metabolism; Transcription factor involved in regulation of membrane lipid biosynthesis by repressing genes involved in fatty acid and phospholipid metabolism. Binds to the 5'-TTAGTANNNNNTANTAA-3' consensus sequence found in the promoter of fabHAF operon (containing fabHA and fabF genes), yhdO and fapR genes and prevents their expression. Its action is probably modulated by malonyl-CoA.
     
 0.571
xre
Phage PBSX transcriptional regulator; Repressor of PBSX. Binds to four sites close to its own gene. Necessary for the maintenance of the lysogenic state.
   
  
 0.545
yjdF
Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 20139185.
  
  
 0.537
yybC
Putative integral membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane component.
  
     0.537
Your Current Organism:
Bacillus subtilis 168
NCBI taxonomy Id: 224308
Other names: B. subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis 168, Bacillus subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis str. BGSC 1A700
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