STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yfhCPutative oxidoreductase (nitroreductase family); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (194 aa)    
Predicted Functional Partners:
yfiY
Putative iron(III) dicitrate transporter binding lipoprotein; Part of the ABC transporter complex YfiYZ/YfhA/YusV involved in import of the iron-hydroxamate siderophores schizokinen, arthrobactin and corprogen. Binds the siderophores and delivers them to the surface of YfiZ/YfhA (Probable).
  
    0.726
yfhB
Putative isomerase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the PhzF family.
 
    0.688
birA
Biotin acetyl-CoA-carboxylase ligase and biotin regulon repressor; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
  
    0.645
yxeB
ABC transporter (ferrioxamine binding lipoprotein); Part of the ABC transporter complex FhuCBGD involved in iron(3+)-hydroxamate import. Binds the iron(3+)-hydroxamate complex and transfers it to the membrane-bound permease. Partially required for the transport of desferrioxamine.
  
    0.645
fhuD
Ferrichrome ABC transporter (ferrichrome-binding lipoprotein); Part of the ABC transporter complex FhuCBGD involved in iron(3+)-hydroxamate import. Binds the iron(3+)-hydroxamate complex and transfers it to the membrane-bound permease. Required for the transport of ferrichrome and coprogen.
  
    0.644
ykuP
Short-chain flavodoxin; Low-potential electron donor to a number of redox enzymes. Belongs to the flavodoxin family.
  
  
 0.623
yclQ
Putative iron-siderophore ABC transporter (binding lipoprotein); Part of the ABC transporter complex YclNOPQ involved in uptake of ferric-petrobactin. Petrobactin is a photoreactive 3,4- catecholate siderophore produced by many members of the B.cereus group, including B.anthracis. Binds selectively iron-free and ferric petrobactin and the petrobactin precursor 3,4-dihydroxybenzoic acid (3,4-DHB); Belongs to the bacterial solute-binding protein 8 family.
  
    0.590
yusV
iron(III)-siderophore transporter (ATP binding component); Provides the ATPase subunit for at least 2 ABC transporter complexes; YfiYZ/YfhA/YusV involved in import of the iron-hydroxamate siderophores schizokinen, arthrobactin and corprogen (Probable), and FeuABC/YusV involved in import of the catecholate siderophores bacillibactin and enterobactin (Probable). Probably responsible for energy coupling to the transport system (By similarity).
  
  
 0.587
dhbA
2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type e: enzyme; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
   0.550
ykuN
Short-chain flavodoxin; Low-potential electron donor to a number of redox enzymes. Belongs to the flavodoxin family.
  
  
 0.540
Your Current Organism:
Bacillus subtilis 168
NCBI taxonomy Id: 224308
Other names: B. subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis 168, Bacillus subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis str. BGSC 1A700
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