Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
yhcEPutative integral inner membrane orphan protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane component. (253 aa)    
Predicted Functional Partners:
yhcG
Putative ABC transporter ATP-binding protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter; Belongs to the ABC transporter superfamily.
  
    0.973
yhcF
Putative transcriptional regulator (GntR family); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: putative regulator.
  
    0.954
yhcH
Putative ABC transporter (ATP-binding protein); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter; Belongs to the ABC transporter superfamily.
  
    0.946
yhcI
Putative ABC transporter (permease); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.
  
    0.907
yhcD
Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
  
    0.774
yhcC
Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
       0.773
yhcB
NADH:quinone oxidoreductase associated to stress; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type e: enzyme.
       0.746
yhcA
Putative exporter; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.
  
    0.679
yhbJ
Putative integral membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane component.
  
    0.565
yhbI
Putative transcriptional regulator (MarR family); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: putative regulator.
  
    0.487
Your Current Organism:
Bacillus subtilis 168
NCBI taxonomy Id: 224308
Other names: B. subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis 168, Bacillus subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis str. BGSC 1A700
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