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srtA protein (Bacillus subtilis) - STRING interaction network
"srtA" - Uncharacterized protein YhcS in Bacillus subtilis
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Score
srtAUncharacterized protein YhcS; Evidence 1a- Function experimentally demonstrated in the studied strain; Product type e- enzyme (198 aa)    
Predicted Functional Partners:
yhcR
Endonuclease YhcR; Sugar-nonspecific endonuclease that yields nucleotide 3’-monophosphate products. No 5’-nucleotidase activity was detected, using 5’-AMP as the substrate, in the presence of diverse divalent metals and with various pH values (1217 aa)
 
     
  0.990
ywpE
Putative cysteine protease YwpE; Evidence 3- Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe- putative enzyme; Belongs to the peptidase C60 family (102 aa)
           
  0.971
secA
Protein translocase subunit SecA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family (841 aa)
           
  0.803
yfkN
Trifunctional nucleotide phosphoesterase protein YfkN; Catalyzes the release of inorganic phosphate from 2’,3’- cyclic nucleotides through consecutive 2’,3’-phosphodiesterase and 3’- (or 2’) nucleotidase activities. Also possesses a 5’- nucleotidase activity. Does not catalyze the release of inorganic phosphate from 3’,5’-cyclic nucleotides. Probably plays a role in the cellular reprocessing of nucleotides present in the medium, under conditions of phosphate shortage (1462 aa)
         
  0.784
htrA
Serine protease Do-like HtrA; Degrades abnormal exported proteins and responsible for the propeptide processing of a natural pro-protein and for the maturation of a native protein. It also plays a prominent role in stress (heat shock, ethanol, puromycin and NaCl) resistance during active exponential growth (Probable); Belongs to the peptidase S1C family (449 aa)
           
  0.743
yhcZ
Uncharacterized transcriptional regulatory protein YhcZ; Member of the two-component regulatory system YhcY/YhcZ (214 aa)
           
  0.683
yhcY
Sensor histidine kinase YhcY; Member of the two-component regulatory system YhcY/YhcZ. Probably activates YhcZ by phosphorylation (379 aa)
           
  0.683
lspA
Lipoprotein signal peptidase; This protein specifically catalyzes the removal of signal peptides from prolipoproteins (154 aa)
           
  0.621
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (353 aa)
           
  0.617
yhcQ
Spore coat protein F-like protein YhcQ; Evidence 4- Homologs of previously reported genes of unknown function (217 aa)
              0.604
Your Current Organism:
Bacillus subtilis
NCBI taxonomy Id: 224308
Other names: B. subtilis subsp. subtilis str. 168, Bacillus subtilis, Bacillus subtilis 168, Bacillus subtilis subsp. subtilis 168, Bacillus subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis str. BGSC 1A700
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