STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yhzDConserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. (61 aa)    
Predicted Functional Partners:
ytpI
Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
  
    0.750
atpI
ATP synthase (subunit i); A possible function for this protein is to guide the assembly of the membrane sector of the ATPase enzyme complex; Belongs to the bacterial AtpI family.
  
     0.722
hmoB
Heme-degrading monooxygenase; Catalyzes the oxidative degradation of the heme macrocyclic porphyrin ring in the presence of a suitable electron donor such as ascorbate or NADPH--cytochrome P450 reductase, with subsequent release of free iron; Belongs to the antibiotic biosynthesis monooxygenase family.
  
     0.719
yhaQ
Na+-efflux ABC transporter (ATP-binding protein); Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; transporter.
       0.701
yhaP
Na+ exporter (ABC permease); Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type t: transporter; To M.jannaschii MJ1024.
       0.701
yojO
Putative activator of nitric oxide reductase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: putative regulator.
  
     0.688
comK
Competence transcription factor (CTF); A master regulator required for the expression of late competence genes including comC, comE, comG and the bdbDC operon. Receives signals from SrfA, and possibly other regulatory COM genes, and transduces these signals to the late COM genes. Represses transcription of rok. May repress expression of a few genes.
  
     0.661
yitV
Putative hydrolase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
  
     0.637
yozC
Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
  
     0.633
ylxL
Coupling factor for flagellin transcription and translation; Required for swarming motility and for maximal sigma-D activity.
  
     0.624
Your Current Organism:
Bacillus subtilis 168
NCBI taxonomy Id: 224308
Other names: B. subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis 168, Bacillus subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis str. BGSC 1A700
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