STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yhaLSporulation factor; Required for efficient sporulation. (70 aa)    
Predicted Functional Partners:
yjaV
Putative NAD(P) binding enzyme; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
   
  
 0.979
ydcC
Putative lipoprotein; required for efficient sporulation.
   
  
 0.836
yhaM
3'-5' exonuclease; Shows a 3'-5' exoribonuclease activity as well as single- stranded DNA 3'-5'exonuclease activity. Plays a role in the secondary pathway of 23S rRNA 3' end maturation; Belongs to the YhaM family.
     
 0.738
nrnB
Oligoribonuclease (nanoRNase); Degrades RNA oligonucleotides with a length of 5 nucleotides in a 3'- to 5'-direction. Less active on shorter RNA oligonucleotides and on those with a length of 24 nucleotides. Prefers RNA oligonucleotides containing adenines rather than cytosines.
      
 0.731
yhbH
Factor involved in shape determination (sporulation); Evidence 1a: Function experimentally demonstrated in the studied strain; Product type f: factor.
   
  
 0.675
yhaO
Putative exonuclease; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the metallophosphoesterase superfamily.
     
 0.657
yqfD
Stage IV sporulation protein; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type cp: cell process.
   
  
 0.620
gerM
Germination (cortex hydrolysis) and sporulation (stage II, multiple polar septa) lytic enzyme; Unknown. Affects both sporulation and germination.
   
    0.501
nrnA
Oligoribonuclease (nanoRNAse), 3',5'-bisphosphate nucleotidase; Bifunctional enzyme which has both oligoribonuclease and pAp- phosphatase activities. Degrades RNA and DNA oligonucleotides with a length of 5 nucleotides and shorter, with a preference for 3-mers. Directionality is controversial; shown to degrade 5-mers and less in a 3' to 5' direction , and 11-mers in a 5' to 3' direction. Converts 3'(2')-phosphoadenosine 5'- phosphate (PAP) to AMP.
      
 0.476
sbcE
ATPase involved in DNA double strand break repair and recombination; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme.
       0.463
Your Current Organism:
Bacillus subtilis 168
NCBI taxonomy Id: 224308
Other names: B. subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis 168, Bacillus subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis str. BGSC 1A700
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