STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
yhaLSporulation factor; Required for efficient sporulation. (70 aa)    
Predicted Functional Partners:
yjaV
Putative NAD(P) binding enzyme; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
   
  
 0.979
ydcC
Putative lipoprotein; required for efficient sporulation.
   
  
 0.878
yhaM
3'-5' exonuclease; Shows a 3'-5' exoribonuclease activity as well as single- stranded DNA 3'-5'exonuclease activity. Plays a role in the secondary pathway of 23S rRNA 3' end maturation; Belongs to the YhaM family.
  
  
 0.827
yhaO
Putative exonuclease; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the metallophosphoesterase superfamily.
     
 0.789
yhbH
Factor involved in shape determination (sporulation); Evidence 1a: Function experimentally demonstrated in the studied strain; Product type f: factor.
   
  
 0.765
nrnB
Oligoribonuclease (nanoRNase); Degrades RNA oligonucleotides with a length of 5 nucleotides in a 3'- to 5'-direction. Less active on shorter RNA oligonucleotides and on those with a length of 24 nucleotides. Prefers RNA oligonucleotides containing adenines rather than cytosines.
      
 0.741
yqfD
Stage IV sporulation protein; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type cp: cell process.
   
  
 0.726
sbcE
ATPase involved in DNA double strand break repair and recombination; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme.
  
    0.614
yhaP
Na+ exporter (ABC permease); Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type t: transporter; To M.jannaschii MJ1024.
       0.546
yhzD
Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
       0.526
Your Current Organism:
Bacillus subtilis 168
NCBI taxonomy Id: 224308
Other names: B. subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis 168, Bacillus subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis str. BGSC 1A700
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