STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yhfEPutative endoglucanase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme. (346 aa)    
Predicted Functional Partners:
yktB
Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; Belongs to the UPF0637 family.
  
  
 0.868
yhfF
Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
  
    0.818
ydbP
Putative thioredoxin or thiol-disulfide isomerase; Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions; Belongs to the thioredoxin family.
   
  
 0.771
lplJ
Lipoate-protein ligase; Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes. Is also able to use octanoate as substrate.
   
  
 0.768
yxeB
ABC transporter (ferrioxamine binding lipoprotein); Part of the ABC transporter complex FhuCBGD involved in iron(3+)-hydroxamate import. Binds the iron(3+)-hydroxamate complex and transfers it to the membrane-bound permease. Partially required for the transport of desferrioxamine.
     
 0.750
ykuP
Short-chain flavodoxin; Low-potential electron donor to a number of redox enzymes. Belongs to the flavodoxin family.
      
 0.680
yusV
iron(III)-siderophore transporter (ATP binding component); Provides the ATPase subunit for at least 2 ABC transporter complexes; YfiYZ/YfhA/YusV involved in import of the iron-hydroxamate siderophores schizokinen, arthrobactin and corprogen (Probable), and FeuABC/YusV involved in import of the catecholate siderophores bacillibactin and enterobactin (Probable). Probably responsible for energy coupling to the transport system (By similarity).
      
 0.605
ykuN
Short-chain flavodoxin; Low-potential electron donor to a number of redox enzymes. Belongs to the flavodoxin family.
      
 0.562
ampS
Aminopeptidase; Metal-dependent exopeptidase; Belongs to the peptidase M29 family.
  
  
 0.539
gndA
NADP+-dependent 6-P-gluconate dehydrogenase; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. Is the predominant 6-P-gluconate dehydrogenase isoenzyme in B.subtilis during growth on glucose and gluconate.
   
  
 0.538
Your Current Organism:
Bacillus subtilis 168
NCBI taxonomy Id: 224308
Other names: B. subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis 168, Bacillus subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis str. BGSC 1A700
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