Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
yhfHHypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. (46 aa)    
Predicted Functional Partners:
ywhL
Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
      
 0.740
ydzM
Putative phage protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type h: extrachromosomal origin.
      
 0.717
yopU
Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
   
  
 0.717
youB
Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 10931276.
      
 0.717
yomL
Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
      
 0.697
lplJ
Lipoate-protein ligase; Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes. Is also able to use octanoate as substrate.
       0.632
ykbA
Putative amino acid permease; Exhibits an obligate exchange activity for serine, threonine and aromatic amino acids.
      
 0.621
yhfI
Putative metal-dependent hydrolase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
       0.599
ytkA
Putative lipoprotein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type lp: lipoprotein.
   
  
 0.569
ydhE
Putative glycosyltransferase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the UDP-glycosyltransferase family.
      
 0.564
Your Current Organism:
Bacillus subtilis 168
NCBI taxonomy Id: 224308
Other names: B. subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis 168, Bacillus subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis str. BGSC 1A700
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