STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yisQPutative Na+driven efflux transporter; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter. (455 aa)    
Predicted Functional Partners:
yisR
Putative transcriptional regulator (AraC/XylS family); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.
 
   
 0.949
ydgH
Putative membrane component; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative membrane component; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MmpL subfamily.
      
 0.850
yisP
Putative squalene/phytoene synthase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the phytoene/squalene synthase family.
   
 
 0.809
yhbJ
Putative integral membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane component.
      
 0.704
ebrB
Small multidrug efflux transporter; Part of a multidrug efflux pump. Confers resistance to cationic lipophilic dyes such as ethidium bromide, acriflavine, pyronine Y and safranin O. The efflux is probably coupled to an influx of protons (By similarity).
   
  
 0.704
ebrA
Small multidrug resistance efflux transporter; Part of a multidrug efflux pump. Confers resistance to cationic lipophilic dyes such as ethidium bromide, acriflavine, pyronine Y and safranin O. The efflux is probably coupled to an influx of protons (By similarity).
   
  
 0.700
ykkD
Efflux transporter; Probably involved in guanidinium transport. In vitro, confers resistance to a broad range of toxic compounds such as cationic dyes, neutral and anionic antimicrobials.
   
  
 0.692
rpfA
RNA degradation presenting factor (ribosomal protein S1 homolog); Plays a role in sporulation; Belongs to the bacterial ribosomal protein bS1 family.
  
    0.537
degA
Transcriptional regulator (LacI family); Involved in the control of degradation of B.subtilis amidophosphoribosyltransferase (purF). Probably activates the gene for a degradative protease.
       0.504
gapB
Glyceraldehyde-3-phosphate dehydrogenase; Involved in the gluconeogenesis. Catalyzes the oxidative phosphorylation of glyceraldehyde 3-phosphate (G3P) to 1,3- bisphosphoglycerate (BPG) using the cofactor NADP. The first reaction step involves the formation of a hemiacetal intermediate between G3P and a cysteine residue, and this hemiacetal intermediate is then oxidized to a thioester, with concomitant reduction of NADP to NADPH. The reduced NADPH is then exchanged with the second NADP, and the thioester is attacked by a nucleophilic inorganic phosphate to produce BPG; Belongs to the gl [...]
   
  
 0.483
Your Current Organism:
Bacillus subtilis 168
NCBI taxonomy Id: 224308
Other names: B. subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis 168, Bacillus subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis str. BGSC 1A700
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