Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
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yisRPutative transcriptional regulator (AraC/XylS family); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator. (287 aa)    
Predicted Functional Partners:
yisQ
Putative Na+driven efflux transporter; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.
 
   
 0.952
yisS
Putative myo-inositol 2-dehydrogenase; Catalyzes the reversible NAD(+)-dependent oxidation of scyllo-inositol (SI) to 2,4,6/3,5-pentahydroxycyclohexanone (scyllo- inosose or SIS). Is required for SI catabolism that allows B.subtilis to utilize SI as the sole carbon source for growth. Cannot use NADP(+) instead of NAD(+); Belongs to the Gfo/Idh/MocA family.
  
  
 0.871
degA
Transcriptional regulator (LacI family); Involved in the control of degradation of B.subtilis amidophosphoribosyltransferase (purF). Probably activates the gene for a degradative protease.
  
    0.857
yfiF
Putative transcriptional regulator (AraC/XylS family; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.
 
 
 0.805
yulF
Enzyme involved in biofilm formation; Catalyzes the NADPH-dependent reduction of scyllo-inosose (SIS) to scyllo-inositol (SI) in vitro, but is unable to dehydrogenate scyllo-inositol and myo-inositol. Is less efficient than the functional paralog IolW. Under physiological conditions, may primarily function as an NADPH-dependent oxidoreductase that reduces carbonyl group(s) in its substrates. Cannot use NADH instead of NADPH.
   
  
 0.741
ydeC
Putative transcriptional regulator (AraC/XylS family); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.
 
   0.646
ccpB
Transcriptional repressor of carbon supply (LacI family); Transcriptional regulator involved in catabolite repression of several operons.
      
 0.631
kdgR
Kdg operon transcriptional regulator (LacI family); Transcriptional repressor of the kdgRKAT and kduID operons for pectin utilization.
  
   
 0.619
araR
Transcriptional repressor of the ara regulon (LacI family); Transcriptional repressor of the arabinose utilization genes. Also regulates its own expression. Binds to two sequences within the promoters of the araABDLMNPQ-abfA operon and the araE gene, and to one sequence in the araR promoter.
  
   
 0.591
yisP
Putative squalene/phytoene synthase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the phytoene/squalene synthase family.
   
  
 0.573
Your Current Organism:
Bacillus subtilis 168
NCBI taxonomy Id: 224308
Other names: B. subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis 168, Bacillus subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis str. BGSC 1A700
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