STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yitSConserved hypothetical protein; May bind long-chain fatty acids, such as palmitate, and may play a role in lipid transport or fatty acid metabolism. (283 aa)    
Predicted Functional Partners:
yloV
Putative dihydroxyacetone/glyceraldehyde kinase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
 0.993
yitY
Putative FMN/FAD-binding oxidoreductase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
      
 0.911
yjcD
Putative ATP-dependent DNA helicase; May be involved in the generation of recombinogenic substrates for the subsequent action of RecA.
     
 0.850
ycgB
Putative integral inner membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane component.
      
 0.846
yrzI
Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
      
 0.833
yitR
Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
   
  
 0.754
ywrE
Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
      
 0.727
spoIISB
Two-component apoptotic control system component B (antitoxin); Antitoxin component of a type II toxin-antitoxin (TA) system. Antitoxin that binds cognate toxin SpoIISA and neutralizes its toxic activity; unlike most antitoxins it does not seem to be highly labile upon expression in E.coli.
   
  
 0.683
ywrJ
Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 14762006.
      
 0.681
nprB
Extracellular neutral protease B; Protease able to cleave casein in vitro. Belongs to the peptidase M4 family.
      
 0.680
Your Current Organism:
Bacillus subtilis 168
NCBI taxonomy Id: 224308
Other names: B. subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis 168, Bacillus subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis str. BGSC 1A700
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