Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of proteins in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| mecA | rpoE | BSU11520 | BSU37160 | Adaptor protein controlling oligomerization of the AAA+ protein ClpC; Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC. | RNA polymerase (delta subunit); Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling. May function in sigma factor switching. It displaces RNA bound to RNA polymerase in a binary complex; Belongs to the RpoE family. | 0.542 |
| mecA | spxA | BSU11520 | BSU11500 | Adaptor protein controlling oligomerization of the AAA+ protein ClpC; Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC. | Redox-sensitive regulator enzyme; Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development- promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress. Negatively affects competence and sporulation. Its degradation by the MecA/ClpXP complex is needed for competence development; Belongs to the ArsC family. Spx subfamily. | 0.790 |
| mecA | yjbH | BSU11520 | BSU11550 | Adaptor protein controlling oligomerization of the AAA+ protein ClpC; Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC. | Putative thiol management oxidoreductase component; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme. | 0.909 |
| rnpZA | rpoA | BSU14540 | BSU01430 | Omega 1 subunit of RNA polymerase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type f: factor; Belongs to the UPF0356 family. | RNA polymerase (alpha subunit); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.900 |
| rnpZA | rpoB | BSU14540 | BSU01070 | Omega 1 subunit of RNA polymerase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type f: factor; Belongs to the UPF0356 family. | RNA polymerase (beta subunit); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.900 |
| rnpZA | rpoC | BSU14540 | BSU01080 | Omega 1 subunit of RNA polymerase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type f: factor; Belongs to the UPF0356 family. | RNA polymerase (beta' subunit); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.900 |
| rnpZA | rpoE | BSU14540 | BSU37160 | Omega 1 subunit of RNA polymerase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type f: factor; Belongs to the UPF0356 family. | RNA polymerase (delta subunit); Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling. May function in sigma factor switching. It displaces RNA bound to RNA polymerase in a binary complex; Belongs to the RpoE family. | 0.920 |
| rnpZA | rpoZ | BSU14540 | BSU15690 | Omega 1 subunit of RNA polymerase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type f: factor; Belongs to the UPF0356 family. | Omega subunit of RNA polymerase; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity). | 0.947 |
| rnpZA | sigA | BSU14540 | BSU25200 | Omega 1 subunit of RNA polymerase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type f: factor; Belongs to the UPF0356 family. | RNA polymerase major sigma-43 factor (sigma-A); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth; Belongs to the sigma-70 factor family. RpoD/SigA subfamily. | 0.800 |
| rnpZA | spxA | BSU14540 | BSU11500 | Omega 1 subunit of RNA polymerase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type f: factor; Belongs to the UPF0356 family. | Redox-sensitive regulator enzyme; Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development- promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress. Negatively affects competence and sporulation. Its degradation by the MecA/ClpXP complex is needed for competence development; Belongs to the ArsC family. Spx subfamily. | 0.826 |
| rnpZA | yjbH | BSU14540 | BSU11550 | Omega 1 subunit of RNA polymerase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type f: factor; Belongs to the UPF0356 family. | Putative thiol management oxidoreductase component; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme. | 0.713 |
| rpoA | rnpZA | BSU01430 | BSU14540 | RNA polymerase (alpha subunit); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | Omega 1 subunit of RNA polymerase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type f: factor; Belongs to the UPF0356 family. | 0.900 |
| rpoA | rpoB | BSU01430 | BSU01070 | RNA polymerase (alpha subunit); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | RNA polymerase (beta subunit); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.999 |
| rpoA | rpoC | BSU01430 | BSU01080 | RNA polymerase (alpha subunit); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | RNA polymerase (beta' subunit); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.999 |
| rpoA | rpoE | BSU01430 | BSU37160 | RNA polymerase (alpha subunit); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | RNA polymerase (delta subunit); Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling. May function in sigma factor switching. It displaces RNA bound to RNA polymerase in a binary complex; Belongs to the RpoE family. | 0.908 |
| rpoA | rpoZ | BSU01430 | BSU15690 | RNA polymerase (alpha subunit); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | Omega subunit of RNA polymerase; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity). | 0.999 |
| rpoA | sigA | BSU01430 | BSU25200 | RNA polymerase (alpha subunit); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | RNA polymerase major sigma-43 factor (sigma-A); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth; Belongs to the sigma-70 factor family. RpoD/SigA subfamily. | 0.998 |
| rpoA | spxA | BSU01430 | BSU11500 | RNA polymerase (alpha subunit); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | Redox-sensitive regulator enzyme; Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development- promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress. Negatively affects competence and sporulation. Its degradation by the MecA/ClpXP complex is needed for competence development; Belongs to the ArsC family. Spx subfamily. | 0.914 |
| rpoB | rnpZA | BSU01070 | BSU14540 | RNA polymerase (beta subunit); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | Omega 1 subunit of RNA polymerase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type f: factor; Belongs to the UPF0356 family. | 0.900 |
| rpoB | rpoA | BSU01070 | BSU01430 | RNA polymerase (beta subunit); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | RNA polymerase (alpha subunit); DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.999 |
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