Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
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Co-expression
Experiments
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[Homology]
Score
cotTSpore coat protein (inner coat); Inner spore coat protein which seems to play a role in germination. (82 aa)    
Predicted Functional Partners:
yxeE
Inner spore coat protein; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type s: structure.
   
  
 0.936
cotF
Spore coat protein; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type s: structure.
   
  
 0.928
cotW
Spore coat protein (insoluble fraction); Evidence 1a: Function experimentally demonstrated in the studied strain; Product type cp: cell process.
   
  
 0.919
ymaG
Inner spore coat protein; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type cp: cell process.
   
  
 0.883
cotV
Spore coat protein (insoluble fraction); Evidence 1a: Function experimentally demonstrated in the studied strain; Product type cp: cell process.
   
  
 0.879
yeeK
Spore associated protein; Part of the spore coat.
   
  
 0.876
cotB
Spore coat protein (outer); Evidence 1a: Function experimentally demonstrated in the studied strain; Product type s: structure.
   
  
 0.873
cotX
Spore coat protein (insoluble fraction); Evidence 1a: Function experimentally demonstrated in the studied strain; Product type cp: cell process.
   
  
 0.853
cotG
Spore morphogenetic protein; May be a morphogenetic protein that is required for the incorporation of protein CotB into the spore coat.
   
  
 0.853
cotM
Spore coat protein (outer); Involved in spore outer coat assembly. May be part of a cross-linked insoluble skeleton that surrounds the spore, serves as a matrix for the assembly of additional outer coat material, and confers structural stability to the final structure.
   
  
 0.850
Your Current Organism:
Bacillus subtilis 168
NCBI taxonomy Id: 224308
Other names: B. subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis 168, Bacillus subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis str. BGSC 1A700
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