STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yjlCConserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 17015645. (140 aa)    
Predicted Functional Partners:
ndh
NADH dehydrogenase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the NADH dehydrogenase family.
  
  
 0.969
ywcJ
Formate/nitrite transporter; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type t: transporter.
     
 0.892
lctP
L-lactate permease; May play a role in L-lactate transport.
      
 0.830
niaR
Transcriptional repressor of de novo NAD biosynthesis; In the presence of nicotinic acid represses transcription of the nadBCA and nifS-nadR operons. Also binds to DNA upstream of the niaP gene, probably regulating it as well. May bind nicotinic acid.
   
  
 0.490
narG
Nitrate reductase (alpha subunit); The alpha chain is the actual site of nitrate reduction.
      
 0.483
infC
Initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.
   
    0.467
nasA
Putative nitrate transporter; May function as a nitrate transporter.
     
 0.440
yqzE
Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
      
 0.422
rex
Transcription repressor of cydABCD and yjlC-ndh expression; Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.
      
 0.420
pncB
Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family.
   
  
 0.411
Your Current Organism:
Bacillus subtilis 168
NCBI taxonomy Id: 224308
Other names: B. subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis 168, Bacillus subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis str. BGSC 1A700
Server load: medium (42%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.