STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
uxuBFructuronate reductase; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (278 aa)    
Predicted Functional Partners:
uxuA
D-mannonate dehydratase; Catalyzes the dehydration of D-mannonate; Belongs to the mannonate dehydratase family.
  
 0.998
uxaC
Galacturonate isomerase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme.
 
  
 0.958
yjmD
Putative oxidoreductase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
 
  
 0.940
yjmC
Putative oxidoreductase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
  
  
 0.929
exuT
Hexuronate transporter; Aldohexuronate transport system; Belongs to the major facilitator superfamily. Phthalate permease family.
  
  
 0.900
kdgK
2-keto-3-deoxygluconate kinase; Catalyzes the phosphorylation of 2-keto-3-deoxygluconate (KDG) to produce 2-keto-3-deoxy-6-phosphogluconate (KDPG). Belongs to the carbohydrate kinase PfkB family.
 
 
 0.773
kdgA
2-keto-3-deoxygluconate-6-phosphate aldolase; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type e: enzyme.
 
  
 0.726
exuR
Transcriptional regulator (LacI family); Transcriptional repressor for the exu locus which is required for galacturonate utilization.
 
  
 0.701
uxaB
Tagaturonate reductase (altronate oxidoreductase); Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type e: enzyme; Belongs to the mannitol dehydrogenase family. UxaB subfamily.
  
 0.640
yusS
Putative 3-oxoacyl-acyl-carrier protein reductase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
     0.640
Your Current Organism:
Bacillus subtilis 168
NCBI taxonomy Id: 224308
Other names: B. subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis 168, Bacillus subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis str. BGSC 1A700
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