STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dppCDipeptide ABC transporter (permease); Part of the binding-protein-dependent transport system for dipeptides; probably responsible for the translocation of the substrate across the membrane. Is expressed to facilitate adaptation to nutrient deficiency conditions, which also induce sporulation. (320 aa)    
Predicted Functional Partners:
dppB
Dipeptide ABC transporter (permease); Part of the binding-protein-dependent transport system for dipeptides; probably responsible for the translocation of the substrate across the membrane. Is expressed to facilitate adaptation to nutrient deficiency conditions.
 
 0.999
dppD
Dipeptide ABC transporter (ATP-binding protein); Part of the binding-protein-dependent transport system for dipeptides. Probably responsible for energy coupling to the transport system. Expressed to facilitate adaptation to nutrient deficiency conditions, which also induce sporulation; Belongs to the ABC transporter superfamily.
 
 0.999
dppE
Dipeptide ABC transporter (dipeptide-binding lipoprotein); Part of the binding-protein-dependent transport system for dipeptides; probably responsible for the binding of dipeptides with high affinity. Is expressed to facilitate adaptation to nutrient deficiency conditions, which also induce sporulation; Belongs to the bacterial solute-binding protein 5 family.
 
 0.998
ykfD
Putative cell wall oligopeptide ABC transporter (ATP binding protein); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter; Belongs to the ABC transporter superfamily.
  
 0.998
oppD
Oligopeptide ABC transporter (ATP-binding protein); Part of the binding protein-dependent transport system for oligopeptides. Probably responsible for energy coupling to the transport system. Required for sporulation and competence.
  
 0.993
oppF
Oligopeptide ABC transporter (ATP-binding protein); Component of the oligopeptide permease, a binding protein- dependent transport system. Necessary for genetic competence but not sporulation. Probably responsible for energy coupling to the transport system.
  
 0.992
appF
Oligopeptide ABC transporter (ATP-binding protein); This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transporting tripeptides. Probably responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily.
  
 0.991
appD
Oligopeptide ABC transporter (ATP-binding protein); This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transporting tripeptides. Probably responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily.
  
 0.990
dppA
D-alanyl-aminopeptidase; Hydrolyzes N-terminal residues in D-amino acid containing peptides. Among the tested substrates, the highest activities are with D-Ala-D-Ala and D-Ala-Gly-Gly. The physiological role is not clear; Belongs to the peptidase M55 family.
 
  
 0.989
oppB
Oligopeptide ABC transporter (permease); Part of the binding-protein-dependent transport system for oligopeptides; probably responsible for the translocation of the substrate across the membrane. Also required for sporulation and competence.
  
 0.984
Your Current Organism:
Bacillus subtilis 168
NCBI taxonomy Id: 224308
Other names: B. subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis 168, Bacillus subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis str. BGSC 1A700
Server load: low (26%) [HD]