STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ykoTPutative glycosyltransferase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme; Belongs to the glycosyltransferase 2 family. (337 aa)    
Predicted Functional Partners:
ykoS
Putative integral inner membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane component.
 
  
 0.991
ykcB
Putative integral membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane component.
 
  
 0.939
ykoG
Two-component response regulator [YkoH]; Probable member of the two-component regulatory system YkoH/YkoG.
   
  
 0.914
ykoH
Two-component sensor histidine kinase [YkoG]; Probable member of the two-component regulatory system YkoH/YkoG. Potentially phosphorylates YkoG.
   
 
 0.856
yrkP
Two-component response regulator [YrkQ]; Member of the two-component regulatory system YrkQ/YrkP.
   
  
 0.846
yfhO
Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
 
  
 0.809
yclJ
Two-component response regulator [YclK]; Could be member of the two-component regulatory system YclK/YclJ.
      
 0.754
ykoU
ATP-dependent DNA ligase subunit; With Ku forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity (Probable). Probably involved in DNA repair during spore germination. In the N-terminal section; belongs to the LigD polymerase family.
   
  
 0.632
spoVT
Transcriptional regulator; Transcriptional factor that regulates positively or negatively the expression of a large number of forespore-specific sigma G-dependent genes. May provide a mechanism of feedback control that is important for forespore development. SpoVT levels during spore formation have a major impact on the germination and the resistance of the resultant spores. To B.subtilis AbrB and Abh.
   
  
 0.571
yndD
Putative spore germination protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor.
   
    0.502
Your Current Organism:
Bacillus subtilis 168
NCBI taxonomy Id: 224308
Other names: B. subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis 168, Bacillus subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis str. BGSC 1A700
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.