STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sspDSmall acid-soluble spore protein d (minor alpha/beta-type sasp); SASP are bound to spore DNA. They are double-stranded DNA- binding proteins that cause DNA to change to an a-like conformation. They protect the DNA backbone from chemical and enzymatic cleavage and are thus involved in dormant spore's high resistance to UV light (64 aa)    
Predicted Functional Partners:
sspF
Small acid-soluble spore protein f (minor alpha/beta-type sasp); May play some important role in either sporulation or the dormant spore
  
   
 0.921
gpr
Germination protease; Initiates the degradation of small, acid-soluble proteins during spore germination
  
   
 0.746
yabP
Spore protein involved in the shaping of the spore coat; Required for sporulation
  
   
 0.730
sspE
Small acid-soluble spore protein e (minor gamma-type sasp); SASP are proteins degraded in the first minutes of spore germination and provide amino acids for both new protein synthesis and metabolism. These proteins may be involved in dormant spore's high resistance to UV light
      
 0.713
spoVAC
Stage V sporulation protein AC; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type cp: cell process
  
     0.708
cotE
Morphogenic protein required for the assembly of the outer coat of the endospore. Is also a regulatory protein for the expression of cotA, cotB, cotC, cotH and other genes encoding spore outer coat proteins
  
   
 0.703
spoVAEB
Stage V sporulation protein AEB; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type cp: cell process
  
     0.700
spoVAF
Stage V sporulation protein AF; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type cp: cell process
  
   
 0.698
yfkQ
Uncharacterized membrane protein YfkQ; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : putative factor
  
   
 0.678
yndD
Uncharacterized membrane protein YndD; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf : putative factor
  
   
 0.656
Your Current Organism:
Bacillus subtilis
NCBI taxonomy Id: 224308
Other names: B. subtilis subsp. subtilis str. 168, Bacillus subtilis 168, Bacillus subtilis subsp. subtilis 168, Bacillus subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis str. BGSC 1A700
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