Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| epsA | kinD | BSU34370 | BSU13660 | Modulator of protein tyrosine kinase EpsB; Evidence 2b: Function of strongly homologous gene; regulator. | Histidine kinase phosphorylating Spo0A; Phosphorylates the sporulation-regulatory protein spo0F and, to a minor extent, is responsible for heterogeneous expression of spo0A during logarithmical growth. Also phosphorylates spo0A under biofilm growth conditions. | 0.845 |
| epsA | sinI | BSU34370 | BSU24600 | Modulator of protein tyrosine kinase EpsB; Evidence 2b: Function of strongly homologous gene; regulator. | Antagonist of SinR; Acts as an antagonist to SinR. SinI prevents SinR from binding to its target sequence on the gene for AprE. | 0.920 |
| epsA | sinR | BSU34370 | BSU24610 | Modulator of protein tyrosine kinase EpsB; Evidence 2b: Function of strongly homologous gene; regulator. | Master regulator of biofilm formation; Negative as well as positive regulator of alternate developmental processes that are induced at the end of vegetative growth in response to nutrient depletion. Binds to the alkaline protease (aprE) gene at two sites. Also acts as a repressor of the key sporulation gene spo0A. Negatively regulates transcription of the eps operon, which is responsible for the biosynthesis of an exopolysaccharide involved in biofilm formation; therefore it could govern the transition between a state in which bacteria swim or swarm and a state in which bacteria assemb [...] | 0.974 |
| epsA | sipW | BSU34370 | BSU24630 | Modulator of protein tyrosine kinase EpsB; Evidence 2b: Function of strongly homologous gene; regulator. | Type I signal peptidase; Required for the cleavage of the signal sequence of TasA and TapA, which are involved in biofilm formation. Belongs to the peptidase S26B family. | 0.994 |
| epsA | spo0A | BSU34370 | BSU24220 | Modulator of protein tyrosine kinase EpsB; Evidence 2b: Function of strongly homologous gene; regulator. | Response regulator; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with Spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. Repressor of abrB, activator of the spoIIa operon. Binds the DNA sequence 5'-TGNCGAA-3' (0A box). | 0.919 |
| epsA | spo0F | BSU34370 | BSU37130 | Modulator of protein tyrosine kinase EpsB; Evidence 2b: Function of strongly homologous gene; regulator. | Two-component response regulator; Key element in the phosphorelay regulating sporulation initiation. Phosphorylation of spo0B during sporulation initiation. | 0.482 |
| epsA | tapA | BSU34370 | BSU24640 | Modulator of protein tyrosine kinase EpsB; Evidence 2b: Function of strongly homologous gene; regulator. | Lipoprotein for biofilm formation; Required for biofilm formation. Required for the proper anchoring and polymerization of TasA amyloid fibers at the cell surface. Is also a minor component of TasA fibers. | 0.994 |
| kinD | epsA | BSU13660 | BSU34370 | Histidine kinase phosphorylating Spo0A; Phosphorylates the sporulation-regulatory protein spo0F and, to a minor extent, is responsible for heterogeneous expression of spo0A during logarithmical growth. Also phosphorylates spo0A under biofilm growth conditions. | Modulator of protein tyrosine kinase EpsB; Evidence 2b: Function of strongly homologous gene; regulator. | 0.845 |
| kinD | phoP | BSU13660 | BSU29110 | Histidine kinase phosphorylating Spo0A; Phosphorylates the sporulation-regulatory protein spo0F and, to a minor extent, is responsible for heterogeneous expression of spo0A during logarithmical growth. Also phosphorylates spo0A under biofilm growth conditions. | Two-component response regulator; Member of the two-component regulatory system PhoP/PhoR involved in the regulation of alkaline phosphatase genes phoA and phoB and of phosphodiesterase. | 0.739 |
| kinD | sinI | BSU13660 | BSU24600 | Histidine kinase phosphorylating Spo0A; Phosphorylates the sporulation-regulatory protein spo0F and, to a minor extent, is responsible for heterogeneous expression of spo0A during logarithmical growth. Also phosphorylates spo0A under biofilm growth conditions. | Antagonist of SinR; Acts as an antagonist to SinR. SinI prevents SinR from binding to its target sequence on the gene for AprE. | 0.759 |
| kinD | sinR | BSU13660 | BSU24610 | Histidine kinase phosphorylating Spo0A; Phosphorylates the sporulation-regulatory protein spo0F and, to a minor extent, is responsible for heterogeneous expression of spo0A during logarithmical growth. Also phosphorylates spo0A under biofilm growth conditions. | Master regulator of biofilm formation; Negative as well as positive regulator of alternate developmental processes that are induced at the end of vegetative growth in response to nutrient depletion. Binds to the alkaline protease (aprE) gene at two sites. Also acts as a repressor of the key sporulation gene spo0A. Negatively regulates transcription of the eps operon, which is responsible for the biosynthesis of an exopolysaccharide involved in biofilm formation; therefore it could govern the transition between a state in which bacteria swim or swarm and a state in which bacteria assemb [...] | 0.752 |
| kinD | sipW | BSU13660 | BSU24630 | Histidine kinase phosphorylating Spo0A; Phosphorylates the sporulation-regulatory protein spo0F and, to a minor extent, is responsible for heterogeneous expression of spo0A during logarithmical growth. Also phosphorylates spo0A under biofilm growth conditions. | Type I signal peptidase; Required for the cleavage of the signal sequence of TasA and TapA, which are involved in biofilm formation. Belongs to the peptidase S26B family. | 0.839 |
| kinD | spo0A | BSU13660 | BSU24220 | Histidine kinase phosphorylating Spo0A; Phosphorylates the sporulation-regulatory protein spo0F and, to a minor extent, is responsible for heterogeneous expression of spo0A during logarithmical growth. Also phosphorylates spo0A under biofilm growth conditions. | Response regulator; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with Spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. Repressor of abrB, activator of the spoIIa operon. Binds the DNA sequence 5'-TGNCGAA-3' (0A box). | 0.994 |
| kinD | spo0B | BSU13660 | BSU27930 | Histidine kinase phosphorylating Spo0A; Phosphorylates the sporulation-regulatory protein spo0F and, to a minor extent, is responsible for heterogeneous expression of spo0A during logarithmical growth. Also phosphorylates spo0A under biofilm growth conditions. | Sporulation initiation phosphotransferase; Key element in the phosphorelay regulating sporulation initiation. Acts on spo0A. Mediates reversible phosphoryl transfer from spo0F to spo0A. | 0.847 |
| kinD | spo0F | BSU13660 | BSU37130 | Histidine kinase phosphorylating Spo0A; Phosphorylates the sporulation-regulatory protein spo0F and, to a minor extent, is responsible for heterogeneous expression of spo0A during logarithmical growth. Also phosphorylates spo0A under biofilm growth conditions. | Two-component response regulator; Key element in the phosphorelay regulating sporulation initiation. Phosphorylation of spo0B during sporulation initiation. | 0.997 |
| kinD | tapA | BSU13660 | BSU24640 | Histidine kinase phosphorylating Spo0A; Phosphorylates the sporulation-regulatory protein spo0F and, to a minor extent, is responsible for heterogeneous expression of spo0A during logarithmical growth. Also phosphorylates spo0A under biofilm growth conditions. | Lipoprotein for biofilm formation; Required for biofilm formation. Required for the proper anchoring and polymerization of TasA amyloid fibers at the cell surface. Is also a minor component of TasA fibers. | 0.890 |
| kinD | yclJ | BSU13660 | BSU03750 | Histidine kinase phosphorylating Spo0A; Phosphorylates the sporulation-regulatory protein spo0F and, to a minor extent, is responsible for heterogeneous expression of spo0A during logarithmical growth. Also phosphorylates spo0A under biofilm growth conditions. | Two-component response regulator [YclK]; Could be member of the two-component regulatory system YclK/YclJ. | 0.745 |
| phoP | kinD | BSU29110 | BSU13660 | Two-component response regulator; Member of the two-component regulatory system PhoP/PhoR involved in the regulation of alkaline phosphatase genes phoA and phoB and of phosphodiesterase. | Histidine kinase phosphorylating Spo0A; Phosphorylates the sporulation-regulatory protein spo0F and, to a minor extent, is responsible for heterogeneous expression of spo0A during logarithmical growth. Also phosphorylates spo0A under biofilm growth conditions. | 0.739 |
| sinI | epsA | BSU24600 | BSU34370 | Antagonist of SinR; Acts as an antagonist to SinR. SinI prevents SinR from binding to its target sequence on the gene for AprE. | Modulator of protein tyrosine kinase EpsB; Evidence 2b: Function of strongly homologous gene; regulator. | 0.920 |
| sinI | kinD | BSU24600 | BSU13660 | Antagonist of SinR; Acts as an antagonist to SinR. SinI prevents SinR from binding to its target sequence on the gene for AprE. | Histidine kinase phosphorylating Spo0A; Phosphorylates the sporulation-regulatory protein spo0F and, to a minor extent, is responsible for heterogeneous expression of spo0A during logarithmical growth. Also phosphorylates spo0A under biofilm growth conditions. | 0.759 |
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