STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ykyBConserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. (154 aa)    
Predicted Functional Partners:
nupQ
Permease of ABC guanosine transporter; Part of the binding-protein-dependent transport system. Probably responsible for the translocation of the substrates across the membrane (By similarity).
      
 0.857
ykuC
Putative efflux transporter; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.
  
  
 0.855
yneB
Putative cell division protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type cp: cell process.
  
     0.743
comK
Competence transcription factor (CTF); A master regulator required for the expression of late competence genes including comC, comE, comG and the bdbDC operon. Receives signals from SrfA, and possibly other regulatory COM genes, and transduces these signals to the late COM genes. Represses transcription of rok. May repress expression of a few genes.
  
   
 0.725
yufL
Two-component sensor histidine kinase [YufM]; Member of a two-component regulatory system MalK/MalR. Involved in the activation of maeA, maeN and yflS in presence of malate. Probably activates MalR by phosphorylation.
   
  
 0.716
yaaL
Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
  
     0.713
ykuI
Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
 
    0.700
ypjP
Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
  
    0.694
ypeP
Ribonuclease; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme.
  
    0.677
yozE
Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; Belongs to the UPF0346 family.
  
    0.666
Your Current Organism:
Bacillus subtilis 168
NCBI taxonomy Id: 224308
Other names: B. subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis 168, Bacillus subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis str. BGSC 1A700
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