node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
cca | spbC | BSU22450 | BSU33770 | Trna nucleotidyltransferase (cca-adding enzyme); Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Has no poly(A) polymerase activity | Killing factor sdpc; Produces a 42-residue extracellular sporulation delaying protein (SDP) that collapses the proton motive force (probably both the membrane potential and pH gradient) across the cell membrane, which leads to autolysis; may form a proton channel . Induces the lysis of other B.subtilis cells that have not entered the sporulation pathway, inducing cannibalism to provide a source of nutrients to support sporulation, and at the same time delaying commitment to the energetically expensive and irreversible onset of sporulation . Addition of SDP to liquid cultures halts grow [...] | 0.442 |
cca | yknU | BSU22450 | BSU14320 | Trna nucleotidyltransferase (cca-adding enzyme); Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Has no poly(A) polymerase activity | Uncharacterized ABC transporter ATP-binding protein YknU; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter | 0.438 |
cca | yknV | BSU22450 | BSU14330 | Trna nucleotidyltransferase (cca-adding enzyme); Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Has no poly(A) polymerase activity | Uncharacterized ABC transporter ATP-binding protein YknV; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter | 0.468 |
cca | yknW | BSU22450 | BSU14340 | Trna nucleotidyltransferase (cca-adding enzyme); Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Has no poly(A) polymerase activity | Hypothetical protein; Part of an unusual four-component transporter, which is required for protection against the killing factor SdpC (sporulation- delaying protein). Has a role in the assembly of the YknXYZ complex | 0.722 |
cca | yknX | BSU22450 | BSU14350 | Trna nucleotidyltransferase (cca-adding enzyme); Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Has no poly(A) polymerase activity | Hlyd family secretion protein; Part of an unusual four-component transporter, which is required for protection against the killing factor SdpC (sporulation- delaying protein) | 0.693 |
cca | yknY | BSU22450 | BSU14360 | Trna nucleotidyltransferase (cca-adding enzyme); Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Has no poly(A) polymerase activity | Putative abc transport system atp-binding protein; Part of an unusual four-component transporter, which is required for protection against the killing factor SdpC (sporulation- delaying protein) | 0.723 |
cca | yknZ | BSU22450 | BSU14370 | Trna nucleotidyltransferase (cca-adding enzyme); Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Has no poly(A) polymerase activity | Putative abc transport system permease protein; Part of an unusual four-component transporter, which is required for protection against the killing factor SdpC (sporulation- delaying protein) | 0.711 |
sdpI | spbC | BSU33780 | BSU33770 | Integral membrane regulator of autophagy; Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor/signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane | Killing factor sdpc; Produces a 42-residue extracellular sporulation delaying protein (SDP) that collapses the proton motive force (probably both the membrane potential and pH gradient) across the cell membrane, which leads to autolysis; may form a proton channel . Induces the lysis of other B.subtilis cells that have not entered the sporulation pathway, inducing cannibalism to provide a source of nutrients to support sporulation, and at the same time delaying commitment to the energetically expensive and irreversible onset of sporulation . Addition of SDP to liquid cultures halts grow [...] | 0.776 |
sdpI | yknW | BSU33780 | BSU14340 | Integral membrane regulator of autophagy; Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor/signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane | Hypothetical protein; Part of an unusual four-component transporter, which is required for protection against the killing factor SdpC (sporulation- delaying protein). Has a role in the assembly of the YknXYZ complex | 0.730 |
spbC | cca | BSU33770 | BSU22450 | Killing factor sdpc; Produces a 42-residue extracellular sporulation delaying protein (SDP) that collapses the proton motive force (probably both the membrane potential and pH gradient) across the cell membrane, which leads to autolysis; may form a proton channel . Induces the lysis of other B.subtilis cells that have not entered the sporulation pathway, inducing cannibalism to provide a source of nutrients to support sporulation, and at the same time delaying commitment to the energetically expensive and irreversible onset of sporulation . Addition of SDP to liquid cultures halts grow [...] | Trna nucleotidyltransferase (cca-adding enzyme); Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Has no poly(A) polymerase activity | 0.442 |
spbC | sdpI | BSU33770 | BSU33780 | Killing factor sdpc; Produces a 42-residue extracellular sporulation delaying protein (SDP) that collapses the proton motive force (probably both the membrane potential and pH gradient) across the cell membrane, which leads to autolysis; may form a proton channel . Induces the lysis of other B.subtilis cells that have not entered the sporulation pathway, inducing cannibalism to provide a source of nutrients to support sporulation, and at the same time delaying commitment to the energetically expensive and irreversible onset of sporulation . Addition of SDP to liquid cultures halts grow [...] | Integral membrane regulator of autophagy; Immunity protein that provides protection for the cell against the toxic effects of SDP, its own SdpC-derived killing factor, and that functions as a receptor/signal transduction protein as well. Once SDP accumulates in the extracellular milieu, SdpI binds to SDP, causing sequestration of SdpR at the bacterial membrane | 0.776 |
spbC | yknW | BSU33770 | BSU14340 | Killing factor sdpc; Produces a 42-residue extracellular sporulation delaying protein (SDP) that collapses the proton motive force (probably both the membrane potential and pH gradient) across the cell membrane, which leads to autolysis; may form a proton channel . Induces the lysis of other B.subtilis cells that have not entered the sporulation pathway, inducing cannibalism to provide a source of nutrients to support sporulation, and at the same time delaying commitment to the energetically expensive and irreversible onset of sporulation . Addition of SDP to liquid cultures halts grow [...] | Hypothetical protein; Part of an unusual four-component transporter, which is required for protection against the killing factor SdpC (sporulation- delaying protein). Has a role in the assembly of the YknXYZ complex | 0.902 |
spbC | yknX | BSU33770 | BSU14350 | Killing factor sdpc; Produces a 42-residue extracellular sporulation delaying protein (SDP) that collapses the proton motive force (probably both the membrane potential and pH gradient) across the cell membrane, which leads to autolysis; may form a proton channel . Induces the lysis of other B.subtilis cells that have not entered the sporulation pathway, inducing cannibalism to provide a source of nutrients to support sporulation, and at the same time delaying commitment to the energetically expensive and irreversible onset of sporulation . Addition of SDP to liquid cultures halts grow [...] | Hlyd family secretion protein; Part of an unusual four-component transporter, which is required for protection against the killing factor SdpC (sporulation- delaying protein) | 0.880 |
spbC | yknY | BSU33770 | BSU14360 | Killing factor sdpc; Produces a 42-residue extracellular sporulation delaying protein (SDP) that collapses the proton motive force (probably both the membrane potential and pH gradient) across the cell membrane, which leads to autolysis; may form a proton channel . Induces the lysis of other B.subtilis cells that have not entered the sporulation pathway, inducing cannibalism to provide a source of nutrients to support sporulation, and at the same time delaying commitment to the energetically expensive and irreversible onset of sporulation . Addition of SDP to liquid cultures halts grow [...] | Putative abc transport system atp-binding protein; Part of an unusual four-component transporter, which is required for protection against the killing factor SdpC (sporulation- delaying protein) | 0.886 |
spbC | yknZ | BSU33770 | BSU14370 | Killing factor sdpc; Produces a 42-residue extracellular sporulation delaying protein (SDP) that collapses the proton motive force (probably both the membrane potential and pH gradient) across the cell membrane, which leads to autolysis; may form a proton channel . Induces the lysis of other B.subtilis cells that have not entered the sporulation pathway, inducing cannibalism to provide a source of nutrients to support sporulation, and at the same time delaying commitment to the energetically expensive and irreversible onset of sporulation . Addition of SDP to liquid cultures halts grow [...] | Putative abc transport system permease protein; Part of an unusual four-component transporter, which is required for protection against the killing factor SdpC (sporulation- delaying protein) | 0.881 |
yfiG | yknW | BSU08260 | BSU14340 | Putative metabolite transport protein YfiG; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter | Hypothetical protein; Part of an unusual four-component transporter, which is required for protection against the killing factor SdpC (sporulation- delaying protein). Has a role in the assembly of the YknXYZ complex | 0.713 |
yfiG | yknX | BSU08260 | BSU14350 | Putative metabolite transport protein YfiG; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter | Hlyd family secretion protein; Part of an unusual four-component transporter, which is required for protection against the killing factor SdpC (sporulation- delaying protein) | 0.658 |
yfiG | yknY | BSU08260 | BSU14360 | Putative metabolite transport protein YfiG; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter | Putative abc transport system atp-binding protein; Part of an unusual four-component transporter, which is required for protection against the killing factor SdpC (sporulation- delaying protein) | 0.665 |
yfiG | yknZ | BSU08260 | BSU14370 | Putative metabolite transport protein YfiG; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter | Putative abc transport system permease protein; Part of an unusual four-component transporter, which is required for protection against the killing factor SdpC (sporulation- delaying protein) | 0.668 |
ygaO | yknW | BSU08890 | BSU14340 | Uncharacterized lipoprotein YgaO; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane component | Hypothetical protein; Part of an unusual four-component transporter, which is required for protection against the killing factor SdpC (sporulation- delaying protein). Has a role in the assembly of the YknXYZ complex | 0.721 |