STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yknYPutative ABC transporter (ATP-binding protein); Part of an unusual four-component transporter, which is required for protection against the killing factor SdpC (sporulation- delaying protein). (230 aa)    
Predicted Functional Partners:
yknX
Putative efflux permease; Part of an unusual four-component transporter, which is required for protection against the killing factor SdpC (sporulation- delaying protein).
 
 
 0.999
yknZ
Putative permease; Part of an unusual four-component transporter, which is required for protection against the killing factor SdpC (sporulation- delaying protein).
 
 0.999
yvrN
Putative ABC transporter (ATP-binding protein); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.
 
 0.990
yknW
Putative permease; Part of an unusual four-component transporter, which is required for protection against the killing factor SdpC (sporulation- delaying protein). Has a role in the assembly of the YknXYZ complex.
  
    0.920
ytrF
Metabolite permease; Part of the ABC transporter complex YtrBCDEF that plays a role in acetoin utilization during stationary phase and sporulation.
 
 0.892
yvrP
Putative ABC transporter component; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.
 
 
 0.824
yheI
Probable multidrug resistance ABC transporter ATP-binding/permease protein YheI; Involved in the transport of four structurally unrelated drugs, including doxorubicin and mitoxantrone. Transmembrane domains (TMD) form a pore in the membrane and the ATP-binding domain (NBD) is responsible for energy generation; Belongs to the ABC transporter superfamily.
 
   
0.796
yknV
Putative ABC transporter (ATP-binding protein); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt: putative transporter.
 
   
0.751
yvgM
Putative molybdenum transport permease; could be part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
    
 0.741
sppA
Signal peptide peptidase; Digestion of cleaved signal peptides (By similarity). Required for efficient processing of precursors under conditions of hyper-secretion. Has a preference for leucine-rich substrate peptides. Belongs to the peptidase S49 family.
   
    0.707
Your Current Organism:
Bacillus subtilis 168
NCBI taxonomy Id: 224308
Other names: B. subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis 168, Bacillus subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis str. BGSC 1A700
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