STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
speAArginine decarboxylase; Catalyzes the formation of agmatine from arginine. (490 aa)    
Predicted Functional Partners:
speE
Spermidine synthase; Involved in the cell growth and proliferation. Catalyzes the irreversible transfer of a propylamine group from the amino donor S- adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4- diaminobutane) to yield spermidine (Probable). Belongs to the spermidine/spermine synthase family.
 
 0.993
speB
Agmatinase; Catalyzes the formation of putrescine from agmatine; Belongs to the arginase family. Agmatinase subfamily.
 
 
 0.990
argI
Arginase; Involved in the catabolism of arginine. Belongs to the arginase family.
   
 0.990
nosA
Nitric-oxide synthase; Catalyzes the production of nitric oxide. Belongs to the NOS family. Bacterial NOS oxygenase subfamily.
     
  0.900
speD
S-adenosylmethionine decarboxylase; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine.
 
  
 0.845
argH
Argininosuccinate lyase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme.
     
 0.819
ynbB
Putative C-S lyase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
 
    0.725
yktA
Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 19429628; Belongs to the UPF0223 family.
  
    0.572
hutG
Formiminoglutamate hydrolase; Catalyzes the conversion of N-formimidoyl-L-glutamate to L- glutamate and formamide.
 
   
 0.427
clsB
Cardiolipin synthetase; Involved in the biosynthesis of cardiolipin.
      
 0.424
Your Current Organism:
Bacillus subtilis 168
NCBI taxonomy Id: 224308
Other names: B. subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis 168, Bacillus subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis str. BGSC 1A700
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