STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ylaNConserved hypothetical protein; Essential for cell growth and for normal cell shape. (93 aa)    
Predicted Functional Partners:
ylbF
Putative regulatory protein; Regulates sporulation prior to stage II. Positively controls the competence regulator ComK at a post-transcriptional level. May modulate the translation, stability or activity of ComS. May work together with YmcA to regulate community development.
 
    0.807
ymcA
Master regulator for biofilm formation; May work together with YlbF to regulate community development.
  
    0.763
ftsW
Cell-division protein; Peptidoglycan polymerase that is essential for cell division.
 
  
 0.715
ywhD
Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
  
    0.680
yutD
Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 12770717.
  
     0.618
fur
Transcriptional regulator for iron transport and metabolism; Iron uptake repressor. Acts on the transcription of ferri- siderophore uptake genes.
  
    0.616
ylaL
Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
 
    0.606
ytpQ
Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 12719520, 21949854; Belongs to the UPF0354 family.
  
     0.586
glsB
Glutaminase; Evidence 2b: Function of strongly homologous gene; Product type e: enzyme.
  
    0.565
divIC
Cell-division initiation protein; Required for vegetative and sporulation septum formation. Required for the activation of genes expressed under the control of the sporulation transcription factors sigma F and sigma E.
  
     0.562
Your Current Organism:
Bacillus subtilis 168
NCBI taxonomy Id: 224308
Other names: B. subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis 168, Bacillus subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis str. BGSC 1A700
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