| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| flgM | sigE | BSU35430 | BSU15320 | Anti-sigma factor repressor of sigma(D)-dependent transcription; Allows the coupling of early and late flagellar synthesis through the repression of RNA polymerase sigma-D factor-dependent transcription. | RNA polymerase sporulation-specific sigma-29 factor (sigma-E); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is responsible for the expression of sporulation specific genes. | 0.865 |
| sigE | flgM | BSU15320 | BSU35430 | RNA polymerase sporulation-specific sigma-29 factor (sigma-E); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is responsible for the expression of sporulation specific genes. | Anti-sigma factor repressor of sigma(D)-dependent transcription; Allows the coupling of early and late flagellar synthesis through the repression of RNA polymerase sigma-D factor-dependent transcription. | 0.865 |
| sigE | sigG | BSU15320 | BSU15330 | RNA polymerase sporulation-specific sigma-29 factor (sigma-E); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is responsible for the expression of sporulation specific genes. | RNA polymerase sporulation-specific sigma factor (sigma-G); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is responsible for the expression of sporulation specific genes in the forespore. | 0.936 |
| sigE | spoIIAB | BSU15320 | BSU23460 | RNA polymerase sporulation-specific sigma-29 factor (sigma-E); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is responsible for the expression of sporulation specific genes. | Anti-sigma factor (antagonist of sigma(F)) and serine kinase; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition. | 0.912 |
| sigE | spoIIE | BSU15320 | BSU00640 | RNA polymerase sporulation-specific sigma-29 factor (sigma-E); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is responsible for the expression of sporulation specific genes. | SpoIIAA-phosphate serine phosphatase; Normally needed for pro-sigma E processing during sporulation but can be bypassed in vegetative cells. Activates SpoIIAA by dephosphorylation. | 0.903 |
| sigE | spoIIGA | BSU15320 | BSU15310 | RNA polymerase sporulation-specific sigma-29 factor (sigma-E); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is responsible for the expression of sporulation specific genes. | Protease processing pro-sigma-E; Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR. Belongs to the peptidase U4 family. | 0.990 |
| sigE | spoIIIAA | BSU15320 | BSU24430 | RNA polymerase sporulation-specific sigma-29 factor (sigma-E); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is responsible for the expression of sporulation specific genes. | ATP-binding stage III sporulation protein; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type cp: cell process. | 0.808 |
| sigE | spoIIID | BSU15320 | BSU36420 | RNA polymerase sporulation-specific sigma-29 factor (sigma-E); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is responsible for the expression of sporulation specific genes. | Transcriptional regulator; This protein regulates the transcription of sigK, which encodes mother cell chamber RNA polymerase sigma-factor (sigma K). | 0.797 |
| sigE | spoIIP | BSU15320 | BSU25530 | RNA polymerase sporulation-specific sigma-29 factor (sigma-E); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is responsible for the expression of sporulation specific genes. | Spore autolysin (stage II sporulation); Evidence 1a: Function experimentally demonstrated in the studied strain; Product type cp: cell process. | 0.847 |
| sigE | spoIIR | BSU15320 | BSU36970 | RNA polymerase sporulation-specific sigma-29 factor (sigma-E); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is responsible for the expression of sporulation specific genes. | pro-sigma(E) endopeptidase (stage II sporulation); Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme. | 0.798 |
| sigE | ylmC | BSU15320 | BSU15360 | RNA polymerase sporulation-specific sigma-29 factor (sigma-E); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is responsible for the expression of sporulation specific genes. | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 12429060. | 0.882 |
| sigG | sigE | BSU15330 | BSU15320 | RNA polymerase sporulation-specific sigma factor (sigma-G); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is responsible for the expression of sporulation specific genes in the forespore. | RNA polymerase sporulation-specific sigma-29 factor (sigma-E); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is responsible for the expression of sporulation specific genes. | 0.936 |
| sigG | spoIIAB | BSU15330 | BSU23460 | RNA polymerase sporulation-specific sigma factor (sigma-G); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is responsible for the expression of sporulation specific genes in the forespore. | Anti-sigma factor (antagonist of sigma(F)) and serine kinase; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition. | 0.975 |
| sigG | spoIIE | BSU15330 | BSU00640 | RNA polymerase sporulation-specific sigma factor (sigma-G); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is responsible for the expression of sporulation specific genes in the forespore. | SpoIIAA-phosphate serine phosphatase; Normally needed for pro-sigma E processing during sporulation but can be bypassed in vegetative cells. Activates SpoIIAA by dephosphorylation. | 0.888 |
| sigG | spoIIGA | BSU15330 | BSU15310 | RNA polymerase sporulation-specific sigma factor (sigma-G); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is responsible for the expression of sporulation specific genes in the forespore. | Protease processing pro-sigma-E; Probable aspartic protease that is responsible for the proteolytic cleavage of the RNA polymerase sigma E factor (SigE/spoIIGB) to yield the active peptide in the mother cell during sporulation. Responds to a signal from the forespore that is triggered by the extracellular signal protein SpoIIR. Belongs to the peptidase U4 family. | 0.979 |
| sigG | spoIIIAA | BSU15330 | BSU24430 | RNA polymerase sporulation-specific sigma factor (sigma-G); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is responsible for the expression of sporulation specific genes in the forespore. | ATP-binding stage III sporulation protein; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type cp: cell process. | 0.882 |
| sigG | spoIIID | BSU15330 | BSU36420 | RNA polymerase sporulation-specific sigma factor (sigma-G); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is responsible for the expression of sporulation specific genes in the forespore. | Transcriptional regulator; This protein regulates the transcription of sigK, which encodes mother cell chamber RNA polymerase sigma-factor (sigma K). | 0.948 |
| sigG | spoIIP | BSU15330 | BSU25530 | RNA polymerase sporulation-specific sigma factor (sigma-G); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is responsible for the expression of sporulation specific genes in the forespore. | Spore autolysin (stage II sporulation); Evidence 1a: Function experimentally demonstrated in the studied strain; Product type cp: cell process. | 0.782 |
| sigG | spoIIR | BSU15330 | BSU36970 | RNA polymerase sporulation-specific sigma factor (sigma-G); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is responsible for the expression of sporulation specific genes in the forespore. | pro-sigma(E) endopeptidase (stage II sporulation); Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme. | 0.894 |
| sigG | ylmC | BSU15330 | BSU15360 | RNA polymerase sporulation-specific sigma factor (sigma-G); Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is responsible for the expression of sporulation specific genes in the forespore. | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 12429060. | 0.894 |
