node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
dppA | frlB | BSU12920 | BSU32610 | D-alanyl-aminopeptidase; Hydrolyzes N-terminal residues in D-amino acid containing peptides. Among the tested substrates, the highest activities are with D-Ala-D-Ala and D-Ala-Gly-Gly. The physiological role is not clear; Belongs to the peptidase M55 family. | fructoselysine-6-P-deglycase; Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid. | 0.504 |
dppA | ylmA | BSU12920 | BSU15340 | D-alanyl-aminopeptidase; Hydrolyzes N-terminal residues in D-amino acid containing peptides. Among the tested substrates, the highest activities are with D-Ala-D-Ala and D-Ala-Gly-Gly. The physiological role is not clear; Belongs to the peptidase M55 family. | Putative ABC transporter (ATP-binding protein); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. | 0.767 |
ecfA | ecfAB | BSU01450 | BSU01460 | Energizing coupling factor of ABC influx transporter (ATP-binding protein); ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. | Energizing coupling factor of ABC influx transporter (ATP-binding protein); ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. | 0.996 |
ecfA | thiW | BSU01450 | BSU13220 | Energizing coupling factor of ABC influx transporter (ATP-binding protein); ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. | Thiamine ABC transporter (ATP-binding protein); Part of the ABC transporter complex YkoCDEF that could transport hydroxymethylpyrimidine (HMP) and/or thiamine. Could also transport other HMP-containing products. Responsible for energy coupling to the transport system (Probable). | 0.704 |
ecfA | ylmA | BSU01450 | BSU15340 | Energizing coupling factor of ABC influx transporter (ATP-binding protein); ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. | Putative ABC transporter (ATP-binding protein); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. | 0.581 |
ecfAB | ecfA | BSU01460 | BSU01450 | Energizing coupling factor of ABC influx transporter (ATP-binding protein); ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. | Energizing coupling factor of ABC influx transporter (ATP-binding protein); ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. | 0.996 |
ecfAB | thiW | BSU01460 | BSU13220 | Energizing coupling factor of ABC influx transporter (ATP-binding protein); ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. | Thiamine ABC transporter (ATP-binding protein); Part of the ABC transporter complex YkoCDEF that could transport hydroxymethylpyrimidine (HMP) and/or thiamine. Could also transport other HMP-containing products. Responsible for energy coupling to the transport system (Probable). | 0.703 |
ecfAB | ylmA | BSU01460 | BSU15340 | Energizing coupling factor of ABC influx transporter (ATP-binding protein); ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. | Putative ABC transporter (ATP-binding protein); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. | 0.569 |
frlB | dppA | BSU32610 | BSU12920 | fructoselysine-6-P-deglycase; Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid. | D-alanyl-aminopeptidase; Hydrolyzes N-terminal residues in D-amino acid containing peptides. Among the tested substrates, the highest activities are with D-Ala-D-Ala and D-Ala-Gly-Gly. The physiological role is not clear; Belongs to the peptidase M55 family. | 0.504 |
frlB | ylmA | BSU32610 | BSU15340 | fructoselysine-6-P-deglycase; Catalyzes the conversion of a range of fructosamine 6- phosphates to glucose 6-phosphate and a free amino acid. | Putative ABC transporter (ATP-binding protein); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. | 0.764 |
ilvA | ilvD | BSU21770 | BSU21870 | Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA (By similarity). | Dihydroxy-acid dehydratase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the IlvD/Edd family. | 0.997 |
ilvA | ylmA | BSU21770 | BSU15340 | Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA (By similarity). | Putative ABC transporter (ATP-binding protein); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. | 0.619 |
ilvD | ilvA | BSU21870 | BSU21770 | Dihydroxy-acid dehydratase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the IlvD/Edd family. | Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA (By similarity). | 0.997 |
ilvD | ylmA | BSU21870 | BSU15340 | Dihydroxy-acid dehydratase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the IlvD/Edd family. | Putative ABC transporter (ATP-binding protein); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. | 0.572 |
kapB | ycbM | BSU31460 | BSU02560 | Factor required for KinB signal transduction and activation of the phosphorelay to sporulation; May play a role in the activation or the expression of KinB. | Two-component sensor histidine kinase [YcbL]; Member of the two-component regulatory system YcbM/YcbL. Probably activates YcbL by phosphorylation. | 0.757 |
kapB | ylmA | BSU31460 | BSU15340 | Factor required for KinB signal transduction and activation of the phosphorelay to sporulation; May play a role in the activation or the expression of KinB. | Putative ABC transporter (ATP-binding protein); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. | 0.687 |
thiW | ecfA | BSU13220 | BSU01450 | Thiamine ABC transporter (ATP-binding protein); Part of the ABC transporter complex YkoCDEF that could transport hydroxymethylpyrimidine (HMP) and/or thiamine. Could also transport other HMP-containing products. Responsible for energy coupling to the transport system (Probable). | Energizing coupling factor of ABC influx transporter (ATP-binding protein); ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. | 0.704 |
thiW | ecfAB | BSU13220 | BSU01460 | Thiamine ABC transporter (ATP-binding protein); Part of the ABC transporter complex YkoCDEF that could transport hydroxymethylpyrimidine (HMP) and/or thiamine. Could also transport other HMP-containing products. Responsible for energy coupling to the transport system (Probable). | Energizing coupling factor of ABC influx transporter (ATP-binding protein); ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. | 0.703 |
thiW | ylmA | BSU13220 | BSU15340 | Thiamine ABC transporter (ATP-binding protein); Part of the ABC transporter complex YkoCDEF that could transport hydroxymethylpyrimidine (HMP) and/or thiamine. Could also transport other HMP-containing products. Responsible for energy coupling to the transport system (Probable). | Putative ABC transporter (ATP-binding protein); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. | 0.566 |
ycbM | kapB | BSU02560 | BSU31460 | Two-component sensor histidine kinase [YcbL]; Member of the two-component regulatory system YcbM/YcbL. Probably activates YcbL by phosphorylation. | Factor required for KinB signal transduction and activation of the phosphorelay to sporulation; May play a role in the activation or the expression of KinB. | 0.757 |