node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
acuC | htpG | BSU29710 | BSU39820 | Protein deacetylase; Role in growth and sporulation on acetoin or butanediol. Involved in the breakdown of these compounds used as a carbon source; Belongs to the histone deacetylase family. | Class III heat-shock protein (molecular chaperone); Molecular chaperone. Has ATPase activity. | 0.846 |
acuC | spoVK | BSU29710 | BSU17420 | Protein deacetylase; Role in growth and sporulation on acetoin or butanediol. Involved in the breakdown of these compounds used as a carbon source; Belongs to the histone deacetylase family. | Mother cell sporulation ATPase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type cp: cell process. | 0.905 |
dnaN | holB | BSU00020 | BSU00310 | DNA polymerase III (beta subunit); Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation o [...] | DNA polymerase III delta' subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. | 0.999 |
dnaN | spoVK | BSU00020 | BSU17420 | DNA polymerase III (beta subunit); Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation o [...] | Mother cell sporulation ATPase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type cp: cell process. | 0.863 |
glpK | spoVK | BSU09290 | BSU17420 | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. | Mother cell sporulation ATPase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type cp: cell process. | 0.707 |
holB | dnaN | BSU00310 | BSU00020 | DNA polymerase III delta' subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. | DNA polymerase III (beta subunit); Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation o [...] | 0.999 |
holB | spoVK | BSU00310 | BSU17420 | DNA polymerase III delta' subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. | Mother cell sporulation ATPase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type cp: cell process. | 0.762 |
htpG | acuC | BSU39820 | BSU29710 | Class III heat-shock protein (molecular chaperone); Molecular chaperone. Has ATPase activity. | Protein deacetylase; Role in growth and sporulation on acetoin or butanediol. Involved in the breakdown of these compounds used as a carbon source; Belongs to the histone deacetylase family. | 0.846 |
htpG | spoVK | BSU39820 | BSU17420 | Class III heat-shock protein (molecular chaperone); Molecular chaperone. Has ATPase activity. | Mother cell sporulation ATPase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type cp: cell process. | 0.717 |
spoIIID | spoIVB | BSU36420 | BSU24230 | Transcriptional regulator; This protein regulates the transcription of sigK, which encodes mother cell chamber RNA polymerase sigma-factor (sigma K). | Regulatory membrane-associated serine protease; Plays a central role in the sigma-K checkpoint which coordinates gene expression during the later stages of spore formation. The protease is activated by trans cleavage of the zymogen precursor producing SpoIVB-45 kDa. This undergoes further trimming by cis cleavage to form SpoIVB-43 kDa and SpoIVB-42 kDa. The protease then cleaves the C-terminus of the SpoIVFA metalloprotease activating the latter. | 0.942 |
spoIIID | spoVK | BSU36420 | BSU17420 | Transcriptional regulator; This protein regulates the transcription of sigK, which encodes mother cell chamber RNA polymerase sigma-factor (sigma K). | Mother cell sporulation ATPase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type cp: cell process. | 0.622 |
spoIIID | ylbJ | BSU36420 | BSU15030 | Transcriptional regulator; This protein regulates the transcription of sigK, which encodes mother cell chamber RNA polymerase sigma-factor (sigma K). | Putative factor required for spore cortex formation; Required for spore cortex formation. | 0.861 |
spoIIID | ymxH | BSU36420 | BSU16720 | Transcriptional regulator; This protein regulates the transcription of sigK, which encodes mother cell chamber RNA polymerase sigma-factor (sigma K). | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; Belongs to the YlmC/YmxH family. | 0.796 |
spoIIID | yqfC | BSU36420 | BSU25360 | Transcriptional regulator; This protein regulates the transcription of sigK, which encodes mother cell chamber RNA polymerase sigma-factor (sigma K). | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 12662922. | 0.711 |
spoIVB | spoIIID | BSU24230 | BSU36420 | Regulatory membrane-associated serine protease; Plays a central role in the sigma-K checkpoint which coordinates gene expression during the later stages of spore formation. The protease is activated by trans cleavage of the zymogen precursor producing SpoIVB-45 kDa. This undergoes further trimming by cis cleavage to form SpoIVB-43 kDa and SpoIVB-42 kDa. The protease then cleaves the C-terminus of the SpoIVFA metalloprotease activating the latter. | Transcriptional regulator; This protein regulates the transcription of sigK, which encodes mother cell chamber RNA polymerase sigma-factor (sigma K). | 0.942 |
spoIVB | spoVK | BSU24230 | BSU17420 | Regulatory membrane-associated serine protease; Plays a central role in the sigma-K checkpoint which coordinates gene expression during the later stages of spore formation. The protease is activated by trans cleavage of the zymogen precursor producing SpoIVB-45 kDa. This undergoes further trimming by cis cleavage to form SpoIVB-43 kDa and SpoIVB-42 kDa. The protease then cleaves the C-terminus of the SpoIVFA metalloprotease activating the latter. | Mother cell sporulation ATPase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type cp: cell process. | 0.644 |
spoIVB | ylbJ | BSU24230 | BSU15030 | Regulatory membrane-associated serine protease; Plays a central role in the sigma-K checkpoint which coordinates gene expression during the later stages of spore formation. The protease is activated by trans cleavage of the zymogen precursor producing SpoIVB-45 kDa. This undergoes further trimming by cis cleavage to form SpoIVB-43 kDa and SpoIVB-42 kDa. The protease then cleaves the C-terminus of the SpoIVFA metalloprotease activating the latter. | Putative factor required for spore cortex formation; Required for spore cortex formation. | 0.792 |
spoIVB | ymxH | BSU24230 | BSU16720 | Regulatory membrane-associated serine protease; Plays a central role in the sigma-K checkpoint which coordinates gene expression during the later stages of spore formation. The protease is activated by trans cleavage of the zymogen precursor producing SpoIVB-45 kDa. This undergoes further trimming by cis cleavage to form SpoIVB-43 kDa and SpoIVB-42 kDa. The protease then cleaves the C-terminus of the SpoIVFA metalloprotease activating the latter. | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; Belongs to the YlmC/YmxH family. | 0.673 |
spoIVB | yqfC | BSU24230 | BSU25360 | Regulatory membrane-associated serine protease; Plays a central role in the sigma-K checkpoint which coordinates gene expression during the later stages of spore formation. The protease is activated by trans cleavage of the zymogen precursor producing SpoIVB-45 kDa. This undergoes further trimming by cis cleavage to form SpoIVB-43 kDa and SpoIVB-42 kDa. The protease then cleaves the C-terminus of the SpoIVFA metalloprotease activating the latter. | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 12662922. | 0.746 |
spoVK | acuC | BSU17420 | BSU29710 | Mother cell sporulation ATPase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type cp: cell process. | Protein deacetylase; Role in growth and sporulation on acetoin or butanediol. Involved in the breakdown of these compounds used as a carbon source; Belongs to the histone deacetylase family. | 0.905 |