node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
iolR | mmsA | BSU39770 | BSU39760 | Transcriptional regulator (DeoR family); Iol operon repressor. | Methylmalonate-semialdehyde dehydrogenase; Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively. | 0.973 |
iolR | yktD | BSU39770 | BSU14690 | Transcriptional regulator (DeoR family); Iol operon repressor. | Conserved hypothetical protein; May be involved in polyketide synthesis. | 0.565 |
iolR | ynaE | BSU39770 | BSU17530 | Transcriptional regulator (DeoR family); Iol operon repressor. | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. | 0.487 |
mmsA | iolR | BSU39760 | BSU39770 | Methylmalonate-semialdehyde dehydrogenase; Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively. | Transcriptional regulator (DeoR family); Iol operon repressor. | 0.973 |
mmsA | yktD | BSU39760 | BSU14690 | Methylmalonate-semialdehyde dehydrogenase; Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively. | Conserved hypothetical protein; May be involved in polyketide synthesis. | 0.570 |
mmsA | ynaE | BSU39760 | BSU17530 | Methylmalonate-semialdehyde dehydrogenase; Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively. | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. | 0.489 |
rapI | yktD | BSU05010 | BSU14690 | Response regulator aspartate phosphatase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type r: regulator; Belongs to the RAP family. | Conserved hypothetical protein; May be involved in polyketide synthesis. | 0.483 |
rapI | ynaE | BSU05010 | BSU17530 | Response regulator aspartate phosphatase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type r: regulator; Belongs to the RAP family. | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. | 0.480 |
ribC | ynaE | BSU16670 | BSU17530 | Bifunctional riboflavin kinase FAD synthase; Catalyzes the phosphorylation of riboflavin to FMN followed by the adenylation of FMN to FAD. | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. | 0.680 |
rttL | ynaE | BSU19000 | BSU17530 | Phage toxin ribonuclease; Toxic component of a type II toxin-antitoxin (TA) system. The C-terminus (residues 449-600) has RNase activity, and inhibits growth upon expression in E.coli. In vitro RNase activity and in vivo growth inhibition are neutralized by cognate antitoxin YobK, but not by antitoxins specific to other toxins with the LXG domain. | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. | 0.501 |
thiF | yktD | BSU11700 | BSU14690 | Adenylate transferase and sulfur transferase (thiamine biosynthesis); Catalyzes the adenylation by ATP of the carboxyl group of the C-terminal glycine of sulfur carrier protein ThiS; Belongs to the HesA/MoeB/ThiF family. | Conserved hypothetical protein; May be involved in polyketide synthesis. | 0.630 |
thiF | ynaE | BSU11700 | BSU17530 | Adenylate transferase and sulfur transferase (thiamine biosynthesis); Catalyzes the adenylation by ATP of the carboxyl group of the C-terminal glycine of sulfur carrier protein ThiS; Belongs to the HesA/MoeB/ThiF family. | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. | 0.572 |
yktD | iolR | BSU14690 | BSU39770 | Conserved hypothetical protein; May be involved in polyketide synthesis. | Transcriptional regulator (DeoR family); Iol operon repressor. | 0.565 |
yktD | mmsA | BSU14690 | BSU39760 | Conserved hypothetical protein; May be involved in polyketide synthesis. | Methylmalonate-semialdehyde dehydrogenase; Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively. | 0.570 |
yktD | rapI | BSU14690 | BSU05010 | Conserved hypothetical protein; May be involved in polyketide synthesis. | Response regulator aspartate phosphatase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type r: regulator; Belongs to the RAP family. | 0.483 |
yktD | thiF | BSU14690 | BSU11700 | Conserved hypothetical protein; May be involved in polyketide synthesis. | Adenylate transferase and sulfur transferase (thiamine biosynthesis); Catalyzes the adenylation by ATP of the carboxyl group of the C-terminal glycine of sulfur carrier protein ThiS; Belongs to the HesA/MoeB/ThiF family. | 0.630 |
yktD | ynaE | BSU14690 | BSU17530 | Conserved hypothetical protein; May be involved in polyketide synthesis. | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. | 0.919 |
ynaE | iolR | BSU17530 | BSU39770 | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. | Transcriptional regulator (DeoR family); Iol operon repressor. | 0.487 |
ynaE | mmsA | BSU17530 | BSU39760 | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. | Methylmalonate-semialdehyde dehydrogenase; Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively. | 0.489 |
ynaE | rapI | BSU17530 | BSU05010 | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. | Response regulator aspartate phosphatase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type r: regulator; Belongs to the RAP family. | 0.480 |