Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
xylAXylose isomerase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the xylose isomerase family. (445 aa)    
Predicted Functional Partners:
xylB
Xylulose kinase; Catalyzes the phosphorylation of D-xylulose to D-xylulose 5- phosphate; Belongs to the FGGY kinase family.
 
 
 0.999
xynB
Xylan beta-1,4-xylosidase; Evidence 1a: Function experimentally demonstrated in the studied strain; enzyme; Belongs to the glycosyl hydrolase 43 family.
 
 
 0.996
gutB
Glucitol (sorbitol) dehydrogenase; Polyol dehydrogenase that catalyzes the NAD(+)-dependent oxidation of various sugar alcohols. Is mostly active with D-sorbitol (D-glucitol), xylitol and L-iditol as substrates, leading to the C2- oxidized products D-fructose, D-xylulose and L-sorbose, respectively.
   
 
 0.986
xylR
Transcriptional regulator; Transcriptional repressor of xylose-utilizing enzymes.
 
  
 0.984
araA
L-arabinose isomerase; Catalyzes the conversion of L-arabinose to L-ribulose.
 
  
 0.951
fruA
Phosphotransferase system (PTS) fructose-specific enzyme IIABC component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This system is involved in fructose transport.
   
 
 0.943
gmuE
ROK fructokinase; Seems to be involved in the degradation of glucomannan.
  
 
 0.936
araB
L-ribulokinase; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type e: enzyme; Belongs to the ribulokinase family.
   
  
 0.924
araD
L-ribulose-5-phosphate 4-epimerase; Involved in the degradation of L-arabinose. Catalyzes the interconversion of L-ribulose 5-phosphate (LRu5P) and D-xylulose 5- phosphate (D-Xu5P) via a retroaldol/aldol mechanism (carbon-carbon bond cleavage analogous to a class II aldolase reaction).
  
  
 0.923
rhgZ
Beta-galacturonidase; May play a role in the degradation of rhamnogalacturonan derived from plant cell walls; Belongs to the glycosyl hydrolase 42 family.
    
 0.916
Your Current Organism:
Bacillus subtilis 168
NCBI taxonomy Id: 224308
Other names: B. subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis 168, Bacillus subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis str. BGSC 1A700
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