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alrB protein (Bacillus subtilis) - STRING interaction network
"alrB" - Alanine racemase 2 in Bacillus subtilis
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Predicted Interactions
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alrBAlanine racemase 2; Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids; Belongs to the alanine racemase family (394 aa)    
Predicted Functional Partners:
ddl
D-alanine--D-alanine ligase; Cell wall formation (354 aa)
   
  0.988
dat
D-alanine aminotransferase; Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction. The second half-reaction is the reverse of the first, transferring the amino group from the pyridoxamine to a second alpha-keto acid to form the product D- amino acid via a ping-pong mechanism. This is an important process in the formation of D-alanine and D-glutamate, which are ess [...] (282 aa)
       
  0.980
murF
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily (457 aa)
     
  0.929
ald
Alanine dehydrogenase; Catalyzes the reversible oxidative deamination of L- alanine to pyruvate. This enzyme is a key factor in the assimilation of L-alanine as an energy source through the tricarboxylic acid cycle during sporulation (378 aa)
       
  0.910
dltC
D-alanyl carrier protein; Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC-carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall (78 aa)
       
  0.903
dltA
D-alanine--D-alanyl carrier protein ligase; Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D-alanyl carrier protein (Dcp) DltC. In an ATP- dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall; Belongs to the AT [...] (503 aa)
       
  0.901
racE
Glutamate racemase 1; Provides the (R)-glutamate required for cell wall biosynthesis (272 aa)
 
   
  0.888
alrA
Alanine racemase 1; Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids; Belongs to the alanine racemase family (389 aa)
   
   
0.836
yrpC
Glutamate racemase 2; Provides the (R)-glutamate required for cell wall biosynthesis (265 aa)
 
   
  0.828
cotY
Spore coat protein Y; Evidence 1a- Function experimentally demonstrated in the studied strain; Product type cp- cell process (162 aa)
           
  0.741
Your Current Organism:
Bacillus subtilis
NCBI taxonomy Id: 224308
Other names: B. subtilis subsp. subtilis str. 168, Bacillus subtilis, Bacillus subtilis 168, Bacillus subtilis subsp. subtilis 168, Bacillus subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis str. BGSC 1A700
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