STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yndMPutative integral inner membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane component. (179 aa)    
Predicted Functional Partners:
fosB
Metallothiol transferase; Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor.
 
     0.650
sspH
Small acid-soluble spore protein; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type cp: cell process; Belongs to the SspH family.
  
     0.605
yhcQ
Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
  
    0.553
yuaC
Putative transcriptional regulator; Negatively regulates the expression of the gbsAB and opuB operons. Required to control expression of these genes in response to choline availability. Also required to downregulate glycine betaine production once cellular adjustment to high osmolarity has been achieved; Belongs to the GbsR family.
  
     0.547
tlp
Small acid-soluble spore protein (thioredoxin-like protein); Evidence 1a: Function experimentally demonstrated in the studied strain; Product type f: factor; Belongs to the Tlp family.
  
    0.545
yjbA
Putative nucleic acid binding protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: putative factor; Belongs to the UPF0736 family.
  
     0.532
yugN
Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
  
     0.483
ylaL
Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
  
     0.476
yvbF
Putative transcriptional regulator; Negatively regulates the transcription of the opuC operon. In the absence of GbsR, is also a negative regulator of the opuB operon. Binds to an inverted repeat in the promoter region of the operons.
  
     0.474
ytrI
Protein involved in sporulation; Involved in sporulation.
  
     0.473
Your Current Organism:
Bacillus subtilis 168
NCBI taxonomy Id: 224308
Other names: B. subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis 168, Bacillus subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis str. BGSC 1A700
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.