node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ccdA | ynzD | BSU17930 | BSU17920 | Cytochrome c-type biogenesis protein CcdA; Required for cytochrome c synthesis and stage V of sporulation. Might transfer reducing equivalents across the cytoplasmic membrane, promoting efficient disulfide bond isomerization of proteins localized on the outer surface of the membrane or in the spore coat. | Spo0A-P phosphatase; Aspartyl-phosphate phosphatase which specifically dephosphorylates the sporulation transcription factor Spo0A-P and negatively regulates the sporulation initiation pathway in order to control the proper timing of sporulation. Belongs to the spo0E family. | 0.501 |
kinE | spo0A | BSU13530 | BSU24220 | Two-component sensor histidine kinase; Phosphorylates the sporulation-regulatory protein spo0A under biofilm growth conditions. Also able to weakly phosphorylate spo0F. | Response regulator; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with Spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. Repressor of abrB, activator of the spoIIa operon. Binds the DNA sequence 5'-TGNCGAA-3' (0A box). | 0.992 |
kinE | spo0B | BSU13530 | BSU27930 | Two-component sensor histidine kinase; Phosphorylates the sporulation-regulatory protein spo0A under biofilm growth conditions. Also able to weakly phosphorylate spo0F. | Sporulation initiation phosphotransferase; Key element in the phosphorelay regulating sporulation initiation. Acts on spo0A. Mediates reversible phosphoryl transfer from spo0F to spo0A. | 0.928 |
kinE | spo0E | BSU13530 | BSU13640 | Two-component sensor histidine kinase; Phosphorylates the sporulation-regulatory protein spo0A under biofilm growth conditions. Also able to weakly phosphorylate spo0F. | Negative regulatory phosphatase acting on Spo0A-P (sporulation); Aspartyl-phosphate phosphatase which specifically dephosphorylates the sporulation transcription factor Spo0A-P and negatively regulates the sporulation initiation pathway in order to control the proper timing of sporulation. Belongs to the spo0E family. | 0.761 |
kinE | spo0F | BSU13530 | BSU37130 | Two-component sensor histidine kinase; Phosphorylates the sporulation-regulatory protein spo0A under biofilm growth conditions. Also able to weakly phosphorylate spo0F. | Two-component response regulator; Key element in the phosphorelay regulating sporulation initiation. Phosphorylation of spo0B during sporulation initiation. | 0.998 |
kinE | yisI | BSU13530 | BSU10730 | Two-component sensor histidine kinase; Phosphorylates the sporulation-regulatory protein spo0A under biofilm growth conditions. Also able to weakly phosphorylate spo0F. | Spo0A-P phosphatase; Aspartyl-phosphate phosphatase which specifically dephosphorylates the sporulation transcription factor Spo0A-P and negatively regulates the sporulation initiation pathway in order to control the proper timing of sporulation. Belongs to the spo0E family. | 0.410 |
kinE | ynzD | BSU13530 | BSU17920 | Two-component sensor histidine kinase; Phosphorylates the sporulation-regulatory protein spo0A under biofilm growth conditions. Also able to weakly phosphorylate spo0F. | Spo0A-P phosphatase; Aspartyl-phosphate phosphatase which specifically dephosphorylates the sporulation transcription factor Spo0A-P and negatively regulates the sporulation initiation pathway in order to control the proper timing of sporulation. Belongs to the spo0E family. | 0.504 |
rapB | spo0A | BSU36690 | BSU24220 | Response regulator aspartate phosphatase; Prevents sporulation by dephosphorylating Spo0F. | Response regulator; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with Spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. Repressor of abrB, activator of the spoIIa operon. Binds the DNA sequence 5'-TGNCGAA-3' (0A box). | 0.765 |
rapB | spo0B | BSU36690 | BSU27930 | Response regulator aspartate phosphatase; Prevents sporulation by dephosphorylating Spo0F. | Sporulation initiation phosphotransferase; Key element in the phosphorelay regulating sporulation initiation. Acts on spo0A. Mediates reversible phosphoryl transfer from spo0F to spo0A. | 0.751 |
rapB | spo0E | BSU36690 | BSU13640 | Response regulator aspartate phosphatase; Prevents sporulation by dephosphorylating Spo0F. | Negative regulatory phosphatase acting on Spo0A-P (sporulation); Aspartyl-phosphate phosphatase which specifically dephosphorylates the sporulation transcription factor Spo0A-P and negatively regulates the sporulation initiation pathway in order to control the proper timing of sporulation. Belongs to the spo0E family. | 0.845 |
rapB | spo0F | BSU36690 | BSU37130 | Response regulator aspartate phosphatase; Prevents sporulation by dephosphorylating Spo0F. | Two-component response regulator; Key element in the phosphorelay regulating sporulation initiation. Phosphorylation of spo0B during sporulation initiation. | 0.994 |
rapB | yisI | BSU36690 | BSU10730 | Response regulator aspartate phosphatase; Prevents sporulation by dephosphorylating Spo0F. | Spo0A-P phosphatase; Aspartyl-phosphate phosphatase which specifically dephosphorylates the sporulation transcription factor Spo0A-P and negatively regulates the sporulation initiation pathway in order to control the proper timing of sporulation. Belongs to the spo0E family. | 0.700 |
rapB | ynzD | BSU36690 | BSU17920 | Response regulator aspartate phosphatase; Prevents sporulation by dephosphorylating Spo0F. | Spo0A-P phosphatase; Aspartyl-phosphate phosphatase which specifically dephosphorylates the sporulation transcription factor Spo0A-P and negatively regulates the sporulation initiation pathway in order to control the proper timing of sporulation. Belongs to the spo0E family. | 0.750 |
rapH | spo0A | BSU06830 | BSU24220 | Response regulator aspartate phosphatase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the RAP family. | Response regulator; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with Spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. Repressor of abrB, activator of the spoIIa operon. Binds the DNA sequence 5'-TGNCGAA-3' (0A box). | 0.504 |
rapH | spo0E | BSU06830 | BSU13640 | Response regulator aspartate phosphatase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the RAP family. | Negative regulatory phosphatase acting on Spo0A-P (sporulation); Aspartyl-phosphate phosphatase which specifically dephosphorylates the sporulation transcription factor Spo0A-P and negatively regulates the sporulation initiation pathway in order to control the proper timing of sporulation. Belongs to the spo0E family. | 0.561 |
rapH | spo0F | BSU06830 | BSU37130 | Response regulator aspartate phosphatase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the RAP family. | Two-component response regulator; Key element in the phosphorelay regulating sporulation initiation. Phosphorylation of spo0B during sporulation initiation. | 0.999 |
rapH | yisI | BSU06830 | BSU10730 | Response regulator aspartate phosphatase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the RAP family. | Spo0A-P phosphatase; Aspartyl-phosphate phosphatase which specifically dephosphorylates the sporulation transcription factor Spo0A-P and negatively regulates the sporulation initiation pathway in order to control the proper timing of sporulation. Belongs to the spo0E family. | 0.482 |
rapH | ynzD | BSU06830 | BSU17920 | Response regulator aspartate phosphatase; Evidence 1a: Function experimentally demonstrated in the studied strain; Product type e: enzyme; Belongs to the RAP family. | Spo0A-P phosphatase; Aspartyl-phosphate phosphatase which specifically dephosphorylates the sporulation transcription factor Spo0A-P and negatively regulates the sporulation initiation pathway in order to control the proper timing of sporulation. Belongs to the spo0E family. | 0.485 |
spo0A | kinE | BSU24220 | BSU13530 | Response regulator; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with Spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. Repressor of abrB, activator of the spoIIa operon. Binds the DNA sequence 5'-TGNCGAA-3' (0A box). | Two-component sensor histidine kinase; Phosphorylates the sporulation-regulatory protein spo0A under biofilm growth conditions. Also able to weakly phosphorylate spo0F. | 0.992 |
spo0A | rapB | BSU24220 | BSU36690 | Response regulator; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with Spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. Repressor of abrB, activator of the spoIIa operon. Binds the DNA sequence 5'-TGNCGAA-3' (0A box). | Response regulator aspartate phosphatase; Prevents sporulation by dephosphorylating Spo0F. | 0.765 |