| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ftsL | yneQ | BSU15150 | BSU18050 | Cell-division protein; Essential cell division protein that may play a structural role. Probably involved in the regulation of the timing of cell division. Also required for sporulation. | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. | 0.609 |
| nadE | yneQ | BSU03130 | BSU18050 | Ammonium-dependent NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. | 0.900 |
| tlp | yneP | BSU18030 | BSU18040 | Small acid-soluble spore protein (thioredoxin-like protein); Evidence 1a: Function experimentally demonstrated in the studied strain; Product type f: factor; Belongs to the Tlp family. | acyl-CoA thioesterase; Has acyl-CoA thioesterase activity. | 0.556 |
| tlp | yneQ | BSU18030 | BSU18050 | Small acid-soluble spore protein (thioredoxin-like protein); Evidence 1a: Function experimentally demonstrated in the studied strain; Product type f: factor; Belongs to the Tlp family. | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. | 0.736 |
| topB | yfhJ | BSU04260 | BSU08560 | DNA topoisomerase III; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA su [...] | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. | 0.680 |
| topB | ykyA | BSU04260 | BSU14570 | DNA topoisomerase III; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA su [...] | Putative chromosome partitioning protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor. | 0.481 |
| topB | yneP | BSU04260 | BSU18040 | DNA topoisomerase III; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA su [...] | acyl-CoA thioesterase; Has acyl-CoA thioesterase activity. | 0.452 |
| topB | yneQ | BSU04260 | BSU18050 | DNA topoisomerase III; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA su [...] | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. | 0.680 |
| topB | yneT | BSU04260 | BSU18080 | DNA topoisomerase III; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA su [...] | Putative CoA-binding protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme. | 0.590 |
| yfhJ | topB | BSU08560 | BSU04260 | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. | DNA topoisomerase III; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA su [...] | 0.680 |
| yfhJ | yneP | BSU08560 | BSU18040 | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. | acyl-CoA thioesterase; Has acyl-CoA thioesterase activity. | 0.758 |
| yfhJ | yneQ | BSU08560 | BSU18050 | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. | 0.916 |
| yfhJ | yneT | BSU08560 | BSU18080 | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. | Putative CoA-binding protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme. | 0.913 |
| yfhJ | ynfC | BSU08560 | BSU18110 | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. | 0.818 |
| ykyA | topB | BSU14570 | BSU04260 | Putative chromosome partitioning protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor. | DNA topoisomerase III; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA su [...] | 0.481 |
| ykyA | yneQ | BSU14570 | BSU18050 | Putative chromosome partitioning protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor. | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. | 0.633 |
| ykyA | ywgA | BSU14570 | BSU37590 | Putative chromosome partitioning protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor. | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function; PubMedId: 16855250. | 0.722 |
| yneP | tlp | BSU18040 | BSU18030 | acyl-CoA thioesterase; Has acyl-CoA thioesterase activity. | Small acid-soluble spore protein (thioredoxin-like protein); Evidence 1a: Function experimentally demonstrated in the studied strain; Product type f: factor; Belongs to the Tlp family. | 0.556 |
| yneP | topB | BSU18040 | BSU04260 | acyl-CoA thioesterase; Has acyl-CoA thioesterase activity. | DNA topoisomerase III; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA su [...] | 0.452 |
| yneP | yfhJ | BSU18040 | BSU08560 | acyl-CoA thioesterase; Has acyl-CoA thioesterase activity. | Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. | 0.758 |