node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
guaA | proA | BSU06360 | BSU13130 | Gmp synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP | Glutamate-5-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate | 0.626 |
guaA | proG | BSU06360 | BSU12910 | Gmp synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP | Redundant pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline | 0.727 |
guaA | proH | BSU06360 | BSU18480 | Gmp synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP | Pyrroline-5-carboxylate reductase 1; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline | 0.729 |
guaA | proI | BSU06360 | BSU23800 | Gmp synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP | Pyrroline-5-carboxylate reductase 2; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline | 0.727 |
proA | guaA | BSU13130 | BSU06360 | Glutamate-5-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate | Gmp synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP | 0.626 |
proA | proB | BSU13130 | BSU13120 | Glutamate-5-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate | Glutamate 5-kinase 1; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate | 0.999 |
proA | proG | BSU13130 | BSU12910 | Glutamate-5-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate | Redundant pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline | 0.901 |
proA | proH | BSU13130 | BSU18480 | Glutamate-5-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate | Pyrroline-5-carboxylate reductase 1; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline | 0.978 |
proA | proI | BSU13130 | BSU23800 | Glutamate-5-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate | Pyrroline-5-carboxylate reductase 2; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline | 0.980 |
proA | proJ | BSU13130 | BSU18470 | Glutamate-5-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate | Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate | 0.999 |
proA | putC | BSU13130 | BSU03210 | Glutamate-5-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate | 1-pyrroline-5-carboxylate dehydrogenase; Important for the use of proline as a sole carbon and energy source or a sole nitrogen source | 0.921 |
proA | rocA | BSU13130 | BSU37780 | Glutamate-5-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate | 1-pyrroline-5-carboxylate dehydrogenase; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type e: enzyme | 0.917 |
proB | proA | BSU13120 | BSU13130 | Glutamate 5-kinase 1; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate | Glutamate-5-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate | 0.999 |
proB | proG | BSU13120 | BSU12910 | Glutamate 5-kinase 1; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate | Redundant pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline | 0.859 |
proB | proH | BSU13120 | BSU18480 | Glutamate 5-kinase 1; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate | Pyrroline-5-carboxylate reductase 1; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline | 0.965 |
proB | proI | BSU13120 | BSU23800 | Glutamate 5-kinase 1; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate | Pyrroline-5-carboxylate reductase 2; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline | 0.972 |
proB | proJ | BSU13120 | BSU18470 | Glutamate 5-kinase 1; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate | Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate | 0.836 |
proB | putB | BSU13120 | BSU03200 | Glutamate 5-kinase 1; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate | Proline dehydrogenase 2; Converts proline to delta-1-pyrroline-5-carboxylate. Important for the use of proline as a sole carbon and energy source or a sole nitrogen source | 0.526 |
proB | putC | BSU13120 | BSU03210 | Glutamate 5-kinase 1; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate | 1-pyrroline-5-carboxylate dehydrogenase; Important for the use of proline as a sole carbon and energy source or a sole nitrogen source | 0.920 |
proB | rocA | BSU13120 | BSU37780 | Glutamate 5-kinase 1; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate | 1-pyrroline-5-carboxylate dehydrogenase; Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; Product type e: enzyme | 0.915 |