STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yozNConserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. (87 aa)    
Predicted Functional Partners:
yocN
Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
  
    0.944
spoIIID
Transcriptional regulator; This protein regulates the transcription of sigK, which encodes mother cell chamber RNA polymerase sigma-factor (sigma K).
   
    0.688
cotJA
Component of the inner spore coat; The cotJ operon proteins affect spore coat composition. They are either required for the normal formation of the inner layers of the coat or are themselves structural components of the coat.
   
    0.622
yocM
Putative spore coat protein; Part of the cellular protein quality control system with a specific role in salt stress response. May facilitate protein homeostasis, together with chemical chaperones that accumulate during the salt stress response. Increased levels of YocM protects against both heat and salt stress. In vitro, displays an unusual aggregase chaperone activity.
  
    0.603
cotJB
Component of the inner spore coat; The cotJ operon proteins affect spore coat composition. They are either required for the normal formation of the inner layers of the coat or are themselves structural components of the coat.
   
    0.593
gerQ
Inner spore coat protein; Essential for the localization of CwlJ in the spore coat and for spore germination triggered by calcium and dipicolinic acid (DPA). Its assembly into the spore coat is dependent on the coat morphogenetic proteins CotE and SpoIVA.
   
    0.593
usd
Putative factor required for translation of spoIIID; Required for translation of SpoIIID.
   
    0.589
cotJC
Component of the inner spore coat; The cotJ operon proteins affect spore coat composition. They are either required for the normal formation of the inner layers of the coat or are themselves structural components of the coat.
   
    0.575
yknT
Hypothetical protein; Evidence 5: No homology to any previously reported sequences; PubMedId: 15383836, 15743949.
   
    0.571
yheD
Spore coat associated protein; Involved in sporulation.
   
    0.528
Your Current Organism:
Bacillus subtilis 168
NCBI taxonomy Id: 224308
Other names: B. subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis 168, Bacillus subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis str. BGSC 1A700
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