STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yodMPutative phospholipid phosphatase; Catalyzes the dephosphorylation of phosphatidylglycerophosphate (PGP) to phosphatidylglycerol. Also has undecaprenyl pyrophosphate phosphatase activity, required for the biosynthesis of the lipid carrier undecaprenyl phosphate. (203 aa)    
Predicted Functional Partners:
uppP
Undecaprenyl-diphosphatase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family.
  
  
 0.935
dgkA
Undecaprenol kinase; Catalyzes the phosphorylation of undecaprenol in vitro, which is probably the physiological substrate. Exhibits no detectable activity against other substrates such as monoacylglycerol, ceramide, or diacylglycerol (DAG). Appears indispensable for the maintenance of spore stability and viability in B.subtilis.
  
  
 0.866
bcrC
Undecaprenyl pyrophosphate phosphatase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the BcrC/YbjG family.
     
 0.774
uppS
Undecaprenyl pyrophosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
  
  
 0.748
cdsA
Phosphatidate cytidylyltransferase (CDP-diglyceride synthase); Evidence 2a: Function of homologous gene experimentally demonstrated in an other organism; enzyme.
   
  
 0.700
yodL
Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
  
    0.661
plsC
1-acylglycerol-phosphate (1-acyl-G3P) acyltransferase; Converts lysophosphatidic acid (LPA) into phosphatidic acid (PA) by incorporating an acyl moiety at the 2 position. This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA. Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.
   
 
 0.648
pgsA
CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase; This protein catalyzes the committed step to the synthesis of the acidic phospholipids; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
  
  
 0.623
pksJ
Polyketide synthase of type I; Involved in some intermediate steps for the synthesis of the antibiotic polyketide bacillaene which is involved in secondary metabolism.
  
 0.605
yozD
Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
  
    0.565
Your Current Organism:
Bacillus subtilis 168
NCBI taxonomy Id: 224308
Other names: B. subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis 168, Bacillus subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis str. BGSC 1A700
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