STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yosXConserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. (117 aa)    
Predicted Functional Partners:
yosQ
SPbeta phage endodeoxyribonuclease (homing endonuclease, responsible for intron mobility); A possible homing endonuclease, it is entirely encoded within the YosP intron.
   
  
 0.966
yorZ
Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
   
  
 0.960
yorE
Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
   
  
 0.943
yorM
Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
   
  
 0.942
nrdEB
SPbeta phage ribonucleoside reductase alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity); Belongs to the ribonucleoside diphosphate reductase large chain family.
   
  
 0.938
yxeD
Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
      
 0.847
yosS
SPbeta phage deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family.
   
  
 0.786
yosW
Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
  
    0.772
yosV
Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
  
    0.720
yncF
Deoxyuridine 5'-triphosphate pyrophosphatase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.
      
 0.680
Your Current Organism:
Bacillus subtilis 168
NCBI taxonomy Id: 224308
Other names: B. subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis 168, Bacillus subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis str. BGSC 1A700
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.