STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yorIPutative replicative DNA helicase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme. (504 aa)    
Predicted Functional Partners:
yorJ
Putative DNA replication initiation protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
  
 
 0.955
yorK
Putative single-strand DNA-specific exonuclease; Putative single-stranded-DNA-specific exonuclease.
  
  
 0.905
yorH
Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
  
    0.901
yorG
Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
  
    0.895
yorL
Putative DNA polymerase; Probable DNA polymerase; Belongs to the DNA polymerase type-C family.
  
 
 0.856
yorM
Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
  
    0.819
dnaG
DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
  
 
 0.766
yorF
Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
  
    0.754
nrdEB
SPbeta phage ribonucleoside reductase alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity); Belongs to the ribonucleoside diphosphate reductase large chain family.
  
  
 0.734
yorE
Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
  
    0.713
Your Current Organism:
Bacillus subtilis 168
NCBI taxonomy Id: 224308
Other names: B. subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis 168, Bacillus subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis str. BGSC 1A700
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.