STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yopCConserved hypothetical protein; May be the toxic component of a type II toxin-antitoxin (TA) system. Neutralized by its cognate antitoxin YopB. In the C-terminal section; belongs to the MbcT/ParT/Res family. (442 aa)    
Predicted Functional Partners:
yopD
Putative conserved hypothetical membrane protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pm: putative membrane component.
  
    0.844
yokK
Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
   
    0.623
yopH
Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
   
    0.547
yopB
Putative transcriptional regulator; May be the antitoxin component of a type II toxin-antitoxin (TA) system. Neutralizes the activity of cognate toxin YopC.
  
    0.543
yopQ
Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
   
    0.528
yokG
Putative transposase fragment; Evidence 7: Gene remnant; putative enzyme; Belongs to the cry6A endotoxin family.
   
    0.527
yopI
Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
   
    0.525
yopR
Putative integrase; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
   
    0.510
yokJ
Conserved hypothetical protein; Antitoxin component of a type II toxin-antitoxin (TA) system. Neutralizes the ability to inhibit growth of cognate toxin YokI upon expression in E.coli. Does not have antitoxin activity on other toxins with the LXG toxin domain.
   
    0.503
yopP
Putative phage integrase; Probable recombinase that does not seem to have a role in chromosome dimer resolution per se but rather may have some facilitative role during chromosome partitioning in general. Belongs to the 'phage' integrase family.
   
    0.501
Your Current Organism:
Bacillus subtilis 168
NCBI taxonomy Id: 224308
Other names: B. subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis 168, Bacillus subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis str. BGSC 1A700
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