STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yonPHypothetical protein; Evidence 5: No homology to any previously reported sequences. (64 aa)    
Predicted Functional Partners:
yonR
Putative transcriptional regulator (Xre family); Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pr: putative regulator.
      
 0.917
bhlB
Holin-like bacteriophage SPbeta protein; May be involved in the secretion of the autolysin BlyA; Belongs to the SPP1 holin family.
   
  
 0.904
yomQ
Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
   
  
 0.721
yomH
Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
   
  
 0.707
yomD
Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
   
  
 0.696
yonO
Conserved hypothetical protein; A single subunit DNA-dependent RNA polymerase (RNAP) that catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates (rNTPs) as substrates. The enzyme is more highly processive than the multisubunit RNAP from E.coli but is considerably more error-prone. It has no detectable proof-reading function but can perform pyrophosphorolysis. Transcribes the late genes of the SPbeta prophage starting from yonK (approximately 35 genes are encoded in the prophage downstream from yonK).
  
    0.683
yomJ
Putative phage immunity protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pf: putative factor.
   
  
 0.633
yokD
Aminoglycoside N3'-acetyltransferase; May contribute to antibiotic resistance; Belongs to the antibiotic N-acetyltransferase family.
      
 0.604
mtbP
DNA (cytosine-5-)-methyltransferase; This enzyme methylates the first cytosine within the sequences GGCC and GCNGC; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
   
  
 0.575
yonN
Putative HU-related DNA-binding protein; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions; Belongs to the bacterial histone-like protein family.
  
    0.533
Your Current Organism:
Bacillus subtilis 168
NCBI taxonomy Id: 224308
Other names: B. subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis 168, Bacillus subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis str. BGSC 1A700
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