Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
yonKConserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function. (63 aa)    
Predicted Functional Partners:
yonO
Conserved hypothetical protein; A single subunit DNA-dependent RNA polymerase (RNAP) that catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates (rNTPs) as substrates. The enzyme is more highly processive than the multisubunit RNAP from E.coli but is considerably more error-prone. It has no detectable proof-reading function but can perform pyrophosphorolysis. Transcribes the late genes of the SPbeta prophage starting from yonK (approximately 35 genes are encoded in the prophage downstream from yonK).
   
  
 0.989
yonJ
Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
  
    0.906
yonH
Putative capsid protein; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type ps: putative structure.
   
    0.730
yonC
Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
   
    0.614
yomS
Putative phage-related lytic exoenzyme; Evidence 3: Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pe: putative enzyme.
   
    0.610
yomT
Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
   
    0.606
yonA
Conserved hypothetical protein; Evidence 4: Homologs of previously reported genes of unknown function.
   
    0.602
yonN
Putative HU-related DNA-binding protein; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions; Belongs to the bacterial histone-like protein family.
   
    0.583
yomW
Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
   
    0.566
yorT
Hypothetical protein; Evidence 5: No homology to any previously reported sequences.
   
    0.547
Your Current Organism:
Bacillus subtilis 168
NCBI taxonomy Id: 224308
Other names: B. subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis 168, Bacillus subtilis subsp. subtilis str. 168, Bacillus subtilis subsp. subtilis str. BGSC 1A700
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